Paeoniflorin and paeonol from Paeonia species are promising compounds with anticancer and other pharmacological properties

Eric Wei Chiang Chan

DOI: 10.7324/JAPS.2025.231323Pages: 001-009

Ethnopharmacology and bioactive evidence of medicinal plants for wound healing in Indonesia: A scoping review

Dewa Ayu Swastini, Ronny Martien, Jajah Fachiroh, Agung Endro Nugroho

DOI: 10.7324/JAPS.2025.211952Pages: 010-030

Chemistry, pharmacology, uses, safety studies, and clinical studies of glucosyl hesperidin: An overview

Eric Wei Chiang Chan, Siu Kuin Wong, Hung Tuck Chan

DOI: 10.7324/JAPS.2025.231318Pages: 031-039

α-Mangostin enhances cisplatin activity in drug-resistant breast cancer cells by targeting multidrug resistance-associated protein 2

Chutamas Thepmalee, Nittiya Suwannasom, Krissana Khoothiam, Chonthida Thephinlap, Amnart Onsa-ard, Aussara Panya

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Development of niacinamide loaded elastic liposome as a potential transepidermal delivery system

Waree Tiyaboonchai, Panatda Ngammuangman, Suchiwa Pan-On, Duy Toan Pham

DOI: 10.7324/JAPS.2025.214096Pages: 048-054

Role of physiologically based biopharmaceutics modeling in predicting and circumventing the drug-drug interactions of tyrosine kinase inhibitors with acid-reducing agents

Sivacharan Kollipara, Praveen Sivadasu, S. R. Rashmi, Punna Rao Ravi, Chakravarthi Guntupalli

DOI: 10.7324/JAPS.2025.234298Pages: 055-069

A quality by design approach with comprehensive green analytical chemistry assessment: Development, validation, and application of a high-performance liquid chromatographic method for quantifying meropenem trihydrate in nanosponges and marketed formulations

Ashwini T, Sanjay Garg, Padmaja A. Shenoy, Raghu Chandrashekhar, Yogendra Nayak, Usha Y. Nayak

DOI: 10.7324/JAPS.2025.236517Pages: 070-095

Berberine-enriched copper oxide nano formulation synthesized using Solanum torvum: A strategic advancement in lung cancer therapy and wound healing

Manju Bargavi Sakthivel, Prabhavathy Devi Narayanan Dass, Tharani Munusamy, Nalini Devarajan, Pavithra Amritkumar, Suresh Malchi, Naresh Kumar Kodiganti, Karunanidhi Kannappan

DOI: 10.7324/JAPS.2025.237203Pages: 096-114

Synthesis, in silico, and in vitro pharmacological evaluation of norbornenylpiperazine derivatives as potential ligands for nuclear hormone receptors

Karine Badalyan, Nelly Babayan, Elena Kalita, Narine Grigoryan, Natalya Sarkisyan, Ruzanna Grigoryan, Grigor Arakelov, Alexan Shahkhatuni, Hovhannes Attaryan, Davit Mkrtchyan, Hasmik Khachatryan, Lusine Khondkaryan

DOI: 10.7324/JAPS.2025.230239Pages: 115-127

Design and evaluation of siRNA molecules targeting conserved UL15 sequence in the HSV genome: An in silico and in vitro study

Archana Mahadev Rao, Fayaz Shaik Mohammad, Divyashree Mysore Somashekara, Rakesh R. Rahangdale, Sanskruti Shrenik Patil, Raghu Chandrashekhar Hariharapura

DOI: 10.7324/JAPS.2025.228650Pages: 128-136

Central composite design enabled formulation development, optimization, and characterization of bosutinib monohydrate loaded lipid nanoparticles: Cytotoxicity studies

Dhananjay Panigrahi, Surya Kanta Swain, Bikash Ranjan Jena, Prasanna Parida, Pratap Kumar Sahu

DOI: 10.7324/JAPS.2025.228972Pages: 137-155

Evaluation of treatment outcomes and risk factors of clinical non-improvement in patients with paraquat poisoning: A 10-year retrospective study

Harsimran Kaur, Vijayanarayana Kunhikatta, Shankar M Bakkannavar, Jayaraj Mymbilly Balakrishnan, Girish Thunga

DOI: 10.7324/JAPS.2025.221347Pages: 156-165

Silk fibroin/polymer hybrid nanoparticles as a potential treatment for hair split-ends

Duy Toan Pham, Bao Chau Nguyen, Hien Triet Nguyen, Ngoc Yen Nguyen, Ngoc Huyen Nguyen, Waree Tiyaboonchai

DOI: 10.7324/JAPS.2025.218439Pages: 166-177

Peppermint essential oil nanoliposomes: Innovative formulation for effective hair growth

Arman Suryani, Lutfi Chabib, Annisa Fitria, Siti Nurlina, Erza Ridha Kartika

DOI: 10.7324/JAPS.2025.207281Pages: 178-189

Molecular docking and molecular dynamics simulation of glycyrrhizic acid in multitarget agents as potential inhibitors of respiratory influenza viruses

Aarati Ramesh Supekar, Santosh Bhujbal, Rashmi Yadav

DOI: 10.7324/JAPS.2025.197023Pages: 190-204

Persistent synergistic antiproliferative and apoptosis induction effects of PGV-1 and tamoxifen or 4-hydroxytamoxifen on ER-positive breast cancer cells

Desty Restia Rahmawati, Arief Nurrochmad, Edy Meiyanto, Riris Istighfari Jenie

DOI: 10.7324/JAPS.2025.228633Pages: 205-215

Molecular simulation studies and systems biological approach to identify the target lead compound for the enzyme DNA gyrase

Rajakumari Karuppaiah, Brindha Devi Parthiban, Shanmugapriya Rishikesan, Balamugundan Munusamy, Aravind Kaliyamurthy, Sundar Himalanathan

DOI: 10.7324/JAPS.2025.209927Pages: 216-233

The potential effect of applying scaffold hydroxyapatite derived from Portunus pelagicus crab shells on osteonectin and VEGF-B expression

Meinar Nur Ashrin, Astila Fitriana, Ainy Fitri Nuriyanto, Maretaningtias Dwi Ariani, Michael Josef Kridanto Kamadjaja

DOI: 10.7324/JAPS.2025.210909Pages: 234-239

Development and validation of a reverse phase-high performance liquid chromatography method for estimation of Thiamine diphosphate in whole blood and dried blood spot

Ysphaneendra Mallimoggala, Monalisa Biswas, Nihaal Maripini, Varashree Bolar Suryakanth, Revathi P. Shenoy, Leslie Edward S. Lewis

DOI: 10.7324/JAPS.2025.213923Pages: 240-252

Model integrated evidence approach for rational and safe formulation development: case of alfuzosin prolonged-release tablets

Sivacharan Kollipara, Rajkumar Boddu, Suribabu Bonda, Hariharan Venugopal, Chandra Deb, Pavan Kumar Mittapalli, Anand Arumugam, Sohel Mohammed Khan, Venkat Ramana Naidu

DOI: 10.7324/JAPS.2025.231215Pages: 253-264

LC-HRMS profiling and in vitro total phenolics, total flavonoids, antioxidant and cytotoxicity evaluation on MCF7 breast cancer cell lines of the extracts and fractions of Aerva sanguinolenta from Java, Indonesia

Armansyah Maulana Harahap, Kurnia Agustini, Nuralih Nuralih, Sri Ningsih, Yuli Widyastuti, Anton Bahtiar

DOI: 10.7324/JAPS.2025.227288Pages: 265-276

Investigation of anti-cardiac hypertrophy effects of Andrographis paniculata ethanolic extract by modulating proinflammation and oxidative stress via Nrf2/NF-kB/NLRP3 signaling pathway: In silico and in vitro approaches

Muhamad Rizqy Fadhillah, Heri Wibowo, Arleni Bustami, Dewi Sukmawati, Aryo Tedjo, Nurul Gusti Khatimah, Ippei Shimizu, Wawaimuli Arozal

DOI: 10.7324/JAPS.2025.226923Pages: 277-294

Protective effects of pterostilbene, purpurin, and arbutin on liver damage in diabetic and non-diabetic rodents

Onkar Bedi, Niharika Srivastava, Davinder Parsad, Tanuj Hooda, Amit Lather, Amarjot Kaur Grewal, Thakur Gurjeet Singh, Gulsheen Panesar, Manish Kumar, Pawan Krishan

DOI: 10.7324/JAPS.2025.221655Pages: 295-310