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RP-HPLC method for quantification of cefotaxime sodium by using design of experiment, a green analytical approach: Analytical method development, validation, and application

Akhil Nair, H. Raghu Chandrashekhar, Usha Y. Nayak

DOI: 10.7324/JAPS.2024.192430

Role of alpha-7 nicotinic acetylcholine receptor down-regulation in cyclic nucleotide reduction in memory-related brain regions of Alzheimer’s rats

Sushma Singh, Neetu Agrawal, Ahsas Goyal

DOI: 10.7324/JAPS.2024.206005

Anti-diabetes and anti-breast cancer of bioactive compounds-enriched fractions isolated from hemp (Cannabis sativa L. subsp.)

Thanakorn Damsud, Apiradee Pothipongsa, Chalermpong Saenjum, Jirapast Sichaem

DOI: 10.7324/JAPS.2024.657585

Flavonoid compound of red fruit papua and its derivatives against sars-cov-2 mpro: An in silico approach

Agus Dwi Ananto, Harno Dwi Pranowo, Winarto Haryadi, Niko Prasetyo

DOI: 10.7324/JAPS.2024.177392

Novel nano-cubosomal chlorhexidine for endodontic irrigation: Development, characterization, and performance evaluation against E. faecalis and streptococcal biofilms in human extracted teeth

Sindhu U. Mukthamath, Ruchira Raychaudhuri, Mamatha Ballal, Kalyana C Pentapati, Krishnaraj Somayaji Shirur, Srinivas Mutalik

DOI: 10.7324/JAPS.2024.195780

Unveiling the therapeutic potential of ketamine in depression: A bibliometric analysis and research landscape overview

Norsuhana Omar, Zahiruddin Othman, Ahmad Shahril Abdul Halim, Rozaziana Ahmad, Md Rizman Md Lazin Md Lazim, Nazlahshaniza Shafin, Asma Hayati Ahmad, Rahimah Zakaria

DOI: 10.7324/JAPS.2024.177533

Economic evaluation of fixed-dose drug combinations: A systematic review

Toi Lam Phung, Due The Ong, Nhi T. N. Ngo, Trang Thuy Pham, Ha Thi Nguyen, Khanh N.C. Duong, Mai Thi Ngoc Dang, Matthew James Alcusky, Daniel J. Amante, Hoa L. Nguyen

DOI: 10.7324/JAPS.2024.199087

A design of expert-based development and optimization of voriconazole-loaded aspasomal gel for topical delivery

Shubham Bajirao Patil, Panchakshari Dandagi, Sujay Hulyalkar, Rubeen Dadakalandar Nadaf

DOI: 10.7324/JAPS.2024.173833

Inhibitory effect of ink derived from Indian Loligo duvauceli squid against HIF1α induced angiogenesis

Seyedeh Sara Kamyab, Alpana S. Moghe, Shyam S. Nandi, Sonali A. Sawant

DOI: 10.7324/JAPS.2024.173159

Anti-oxidative constituents of Musa balbisiana Colla fruit extract and evaluation of hepatoprotective activity in CCl₄-induced hepatotoxicity in Swiss albino mice

Nabanita Baruah, Madhubanti Das, Kandarpa Kumar Saikia, Jogen Chandra Kalita

DOI: 10.7324/JAPS.2024.172339

Comparison between solvent evaporation and supercritical CO₂ technology in taste-masking of Azithromycin bitter-taste using pH-sensitive Eudragit EPO or Eudragit S100 polymers

Hadeia Mashaqbeh, Rana Obaidat, Mo’tasem M. Alsmadi, Tamara Athamneh

DOI: 10.7324/JAPS.2024.171403

Standardized mixture of Pluchea indica and Sauropus androgynus extract stimulates the gene expression associated with lactogenesis in rats

Eustachia Diajeng Wandansari, Rul Afiyah Syarif, Dian Eurike Septyaningtrias, Setyo Purwono, Eti Nurwening Sholikhah

DOI: 10.7324/JAPS.2024.164075

Anticancer activity of liposomal formulation co-encapsulated with coumarin and phenyl butyric acid

Ali Allateef, Naeem Shalan, Zainab Lafi

DOI: 10.7324/JAPS.2024.181335

Characterization of functional human insulin produced using the Pichia pastoris expression system

Dini Nurdiani, Eko Wahyu Putro, Endah Puji Septisetyani, Nuruliawaty Utami, Hariyatun Hariyatun, Pekik Wiji Prasetyaningrum, Wien Kusharyoto

DOI: 10.7324/JAPS.2024.180473

Endophytic fungi from red ginger (Zingiber officinale var. rubrum) as promising source of antimicrobial and cytotoxic secondary metabolites

Ni Putu Ariantari, Ni Putu Eka Leliqia, I Putu Yogi Astara Putra, Nadzifa Nugraheni, Riris Istighfari Jenie, Edy Meiyanto

DOI: 10.7324/JAPS.2024.178823

A sensitive liquid chromatography tandem mass spectrometric method development and validation for ribociclib and its formulation

J. Ramesh, B. Babu, R. Sangamithra, D. Anandha Jothi, S.N. Meyyanathan, B. Gowramma

DOI: 10.7324/JAPS.2024.178562

Computational analysis of Salmalia malabarica (Bombax ceiba) for the management of ulcerative colitis

Savita Bhosale, Prashant G. Jadar, Sunil S. Jalalpure, Vishal S. Patil, Kashinath Hiremath

DOI: 10.7324/JAPS.2024.161733

Integrating ligand and structure-based discovery approaches to unravel potential novel glyoxalase-I inhibitors

Roa’a Bani-Khalaf, Qosay Al-Balas, Soraya Alnabulsi

DOI: 10.7324/JAPS.2024.193801

Enhanced bioavailability through quality by design optimization of ceritinib nanostructured lipid carriers: Formulation, characterization, and stability evaluation

Kunchithapatham Janakiraman, Katla Venu Madhav, Sunil Kumar Chaitanya Padavala, Naga Haritha Pamujula

DOI: 10.7324/JAPS.2024.188653

Computational investigation into Parinari curatellifolia flavonoids as lead hepatoprotective therapeutics

Ayodeji Amobonye, Saheed Sabiu, Mary Tolulope Olaleye, Santhosh Pillai

DOI: 10.7324/JAPS.2024.188178

Fermented calabash fruit-derived choline (Crescentia cujete L.) against artificial-induced ischemic stroke in rat models: Analysis of N/LR, PWR, histopathology, GM-CSF, and VEGF

Yos Adi Prakoso, Jasir Hakim Hidayah, Sitarina Widyarini

DOI: 10.7324/JAPS.2024.188046

Isolation and establishment of trans-cinnamic acid as a reference standard from Radix Scrophularia buergeriana Miq

Ngan Nguyen Kim Luu, Ngan My Tran, Phuong Thu Tran, Duong Hoang Trinh

DOI: 10.7324/JAPS.2024.186113

Cost-effectiveness analysis of several dosage regimens of vancomycin in ventilator-associated pneumonia critically ill patients

Bobby Presley, Steven Victoria Halim, Eko Setiawan

DOI: 10.7324/JAPS.2024.194102

Research Trend in The Inhibition of Transient Receptor Potential Vanilloid 1 (TRPV1): Bibliometric Analysis and Visualization

Shereen M. Aleidi, Amani A. Harb, Lina A. Dahabiyeh, Montaha AL-Iede, Islam Hamad, Walhan Alshaer, Ihab M. Almasri, Yasser Bustanji

DOI: 10.7324/JAPS.2024.188749

Diterpene alcohol fraction of Cyperus rotundus Linn essential oil regulates Bcl-2 and Bax expression inducing apoptosis on HeLa in vitro and in silico

Susianti Susianti, Yanwirasti Yanwirasti, Eryati Darwin, Jamsari Jamsari, Arif Setiawansyah

DOI: 10.7324/JAPS.2024.188231

Phytochemical analysis and in vitro investigation of wound healing, cytotoxicity, and inflammatory response in potentially active extracts of Anogeissus dhofarica

Duaa Abuarqoub, Walid Aburayyan, Luay Rashan, Wael Abu Dayyih, Hisham Y. Al-Matubsi

DOI: 10.7324/JAPS.2024.174429

QSAR modeling of isoquinoline derivatives having AKR1C3 inhibitory activity: Lead optimization

Papichettypalle Gopinath, Dwivedi Ashish ranjan, Beda Durgaprasad, Karkara Bidhuhusan, Pathuri Raghuveer, Godela RamReddy, Kasula Ramalingeswara Rao, Dontireddy Ravisankara Reddy, Sibala Subramanyam

DOI: 10.7324/JAPS.2024.160453

SNEDDS to improve the bioactivities of Pandanus tectorius leaves: Optimization, antioxidant, and anticancer activities via apoptosis induction in human cervical cancer cell line

Alifa Husnun Kholieqoh, Murni Nur Islamiah Kassim, Tengku Sifzizul Tengku Muhammad, Khairul Anam, Yeong Yik Sung, Hermansyah Amir, Husna Nugraha Praja, Yosie Andriani

DOI: 10.7324/JAPS.2024.168694

Sorafenib combination with imatinib enhances apoptotic and cell cycle arrest effects with no effect on viability and BCR-ABL expression of K-562 cells

Belal A. Al-Husein, Ahmad Al-Azayzih, Fatema S. Redha

DOI: 10.7324/JAPS.2024.161424

Constituents of carbazole alkaloids and anti-cancer properties of extracts, mahanine, isomahanine, mahanimbine, and girinimbine from Bergera koenigii

Eric Wei Chiang Chan, Siu Kuin Wong

DOI: 10.7324/JAPS.2024.192931

Empirical antibiotics versus definitive antibiotics for Sepsis patients in Indonesia: A cost-effectiveness analysis

Rini Noviyani, Khanh N. C. Duong, Nhi T. N. Ngo, Sanjeewa Kularatna, Agata Widatama, I Gusti Ayu Made Srinadi

DOI: 10.7324/JAPS.2024.195834

Neuroprotective effects of safinamide against autophagy in 6-hydroxydopamine-induced SH-SY5Y cell model of Parkinson’s disease

Yvonne Wei Ping Yeo, Brianna, Yiing Jye Yap, Khuen Yen Ng, Soi Moi Chye, Anna Pick Kiong Ling, Yin Yin Ooi, Yee Lian Tiong, Rhun Yian Koh

DOI: 10.7324/JAPS.2024.142043

Determination of phytochemical markers andrographolide, eugenol and zingerone in nilavembu kudineer by RP-HPLC method

B. Sivagami, B. Sailaja

DOI: 10.7324/JAPS.2024.180359

The effects of combined co-expression of groel/es and trigger factor chaperone towards Thermus thermophilus DNA polymerase enzyme expression on Escherichia coli BL21(DE3)

Iman Permana Maksum, Diandra Firdiani Utami, Sriwidodo Sriwidodo, Ryan Adibagus Haryanto, Riyona Desvy Pratiwi

DOI: 10.7324/JAPS.2024.152923

Ameliorative effect of Vitis gracilis leaf decoction against sensory and motoric disorders, oxidative stress, and cerebellar degeneration in diabetic mice

Putra Santoso, Alfi Yuniarti, Rita Maliza, Alimuddin Tofrizal, Dinda Fadhila Belahusna

DOI: 10.7324/JAPS.2024.174900

Screening of surfactant mixture ratio for preparation of oil-in-water nanoemulsion: A technical note

Shobhit Kumar, Karan Wadhwa, Rakesh Pahwa, Javed Ali, Sanjula Baboota

DOI: 10.7324/JAPS.2024.180648

Suppression of adipogenesis and stimulation of lipolysis by oxyresveratrol and heartwood extract from Artocarpus lacucha in adipocyte culture

Kanittaporn Trisat, Nanteetip Limpeanchob

DOI: 10.7324/JAPS.2024.188627

Exploring the efficacy of the wild mushroom Astraeus hygrometricus extract on lipid profiles, insulin resistance, and oxidative stress in rats fed a high-fat diet

Wathita Phachonpai, Prathakphong Riyamongkol, Dej Mann, Nattakorn Kamkaew

DOI: 10.7324/JAPS.2024.182575

The development of a GC-FID method for indirect quantification of chloroacetyl chloride, a potential genotoxic impurity, in chlordiazepoxide hydrochloride drug substance

Srinivas Birudukota, Bhaskar Mangalapu, Ramesha Andagar Ramakrishna, Swagata Halder, Venkata Narayana Palakollu

DOI: 10.7324/JAPS.2024.182017

Effect of treadmill exercise on the liver, kidney health, and serum IL-10 levels in high-fat diet-induced obese male Wistar rats

Samreen M. Sheik, H. Madhukar Mallya, Deepak Nayak Manel, Karkala Sreedhara Ranganath Pai, Vani Lakshmi Ramesh Iyer, Varashree Bolar Suryakanth, Revathi P. Shenoy

DOI: 10.7324/JAPS.2024.201460

Flux dynamics of C-5 amino acid precursors in fed-batch cultures of Streptomyces clavuligerus during clavulanic acid biosynthesis

Luisa María Gómez-Gaona, Howard Ramírez-Malule, David Gómez-Ríos

DOI: 10.7324/JAPS.2024.191319

Neuroprotective effects of g-Aminobutyric acid-enriched germinated riceberry extract in cerebral ischemic reperfusion-induced cognitive impairment mice

PayungsakTantipaiboonwong, KomsakPintha, NapapanKangwan, DejMann, PrathakphongRiyamongkhol, Watcharaporn Preedapirom Jeefoo

DOI: 10.7324/JAPS.2024.175285

Triplet analysis: Quantifying ivacaftor, tezacaftor, and elexacaftor in plasma with mass spectrometry

Ravikanth Inturi, Srikanth Inturi, David Raju Medepalli, Venkata Basaveswara Rao Mandava

DOI: 10.7324/JAPS.2024.182963

Biological activities of Chrysanthemum morifolium and Chrysanthemum indicum: Molecular prospective

Nur Vaizura Mohamad, Che Nur Mazadillina Che Zahari

DOI: 10.7324/JAPS.2024.171645

Stability-indicating HPLC method optimization using quality by design with design of experiments approach for quantitative estimation of organic related impurities of Doripenem in pharmaceutical formulations

N. V. V. D. Praveen Boppy, Sharath Babu Haridasyam, Niroja Vadagam, Naveen Sara, Karthik Sara, Eswarlal Tamma

DOI: 10.7324/JAPS.2024.190386

The interconnections between gerontogen, aging, and senotherapy

Rahma Rahma, Agian Jeffilano Barinda

DOI: 10.7324/JAPS.2024.184140

The trend of publication about Lumbricus rubellus for periodontitis treatment in the Scopus database: A bibliometric analysis

Lelly Andayasari, Sagung Agung Putri Dwiastuti, I Gusti Agung Ayu Dharmawati, I Putu Suiraoka, Heri Setiyo Bekti, I Gusti Agung Ayu Putu Swastini, Nurhayati, Novia Susianti, Iin Nurlinawati, Made Ayu Lely Suratri, Harimat Hendarwan, Putu Sanna Yustiantara, Eka Indra Setyawan

DOI: 10.7324/JAPS.2024.179572

Cephalosporin C acylase: Important role, obstacles, and strategies to optimize expression in E. coli

Muthi’ah Rasyidah, Sismindari Sismindari, Purwanto Purwanto

DOI: 10.7324/JAPS.2024.179954

Shedding light on Paraconiothyrium brasiliense: Secondary metabolites, biological activities, and computational studies

Sabrin R. M. Ibrahim, Abdulrahim A. Alzain, Fatima A. Elbadwi, Abdulrahman E. Koshak, Aram Hamad AlSaedi, Ahmed Ashour, Wadah Osman, Ikhlas A. Sindi, Selwan M. El-Sayed, Abdelbasset A. Farahat, Ahmed H.E. Hassan, Gamal A. Mohamed

DOI: 10.7324/JAPS.2024.184503

Availability, prices, and affordability of essential medicines in Asia: A systematic review

Muhammad Qowiyul Amin, Susi Ari Kristina, Satibi Satibi

DOI: 10.7324/JAPS.2024.183688

Simultaneous determination of levothyroxine and its metabolite liothyronine in human serum by using LC-ESI-MS/MS and its bioequivalence application

Kanchan Soni, Gopal Prasad Agrawal

DOI: 10.7324/JAPS.2024.187582

Quantification of asciminib by LC-MS/MS method in human plasma: Validation and stability studies

Hema, Naresh Panigrahi

DOI: 10.7324/JAPS.2024.163326

Assessments of anti-breast cancer activity and profiling of active compounds using LC-MS/MS from the Indonesian Agelas nakamurai

Tutik Murniasih, Tri Aryono Hadi, Peni Ahmadi, Martha Sari, Bustanussalam Bustanussalam, Yuni Elsa Hadisaputri, Masteria Yunovilsa Putra, Siti Irma Rahmawati, Dwi Wahyu Indriani

DOI: 10.7324/JAPS.2024.158982