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Journal of Applied
Pharmaceutical Science

ISSN Online: 2231-3354, Frequency: Monthly

Editor in Chief: Prof. Srinivas Mutalik

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Indexed in Scopus [Q2], Cite score: 2.3, SJR: 0.281

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Journal of Applied Pharmaceutical Science is a peer-reviewed, open-access journal, dedicated to the publication of original research, review articles, short communications on applied researches in the following fields of biology such as. Read More.

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Current Acceptance rate: 20%

Submission to a final decision: 52 days

Acceptance to publication: 20 days

CiteScore (2020): 2.0

CiteScore (2021): 2.3

Latest Articles

Online first version of articles that are not yet assigned to an issue

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Research Article     |    2022-07-31


Microbial adaptations at higher altitude for sustainable development: A review

Manali Singh, Kuldeep Jayant, Dipti Singh, Deep Chandra Suyal, Abhirup Mitra [...]
Graphical Abstract

Research Article     |    2023-01-10


Computational simulations of microalgae-derived bioactive compounds as a novel inhibitor against B-Raf V600E-driven melanoma

Fiddy Semba Prasetiya, Wanda Destiarani, Irene Retno Cahya Prihastaningtyas, Mochamad Untung Kurnia Agung, Muhammad Yusuf [...]
Graphical Abstract

Research Article     |    2023-01-10


Formulation and development of novel probiotic-loaded gel for the treatment of caffeine-induced anxiety

Pooja Verma, Rohit Dutt, Siraj Anwar
Graphical Abstract

Research Article     |    2023-01-10


Cytotoxic and antioxidant activities of flavonoids and diterpenoids from Macaranga involucrata (Roxb.) Baill

Alifia Muharram, Diah Ayu Rachmawati, Shola Mardhiyyah, Tjitjik Srie Tjahjandarie, Ratih Dewi Saputri [...]
Graphical Abstract

Research Article     |    2023-01-10


Biological potency of actinomycetes extracts from rhizosphere soil of Dacrycarpus imbricatus from Toba Samosir, North Sumatra

Praptiwi, Ahmad Fathoni, Ade Lia Putri, Dewi Wulansari, Andria Agusta [...]
Graphical Abstract

Research Article     |    2023-01-10


Formulation, development, and in vitro evaluation of a nanoliposomal delivery system for mebendazole and gefitinib

Maram Kutkut, Ashok K. Shakya, Hamdi Nsairat, Mohamed El-Tanani

Graphical Abstract

Research Article     |    2023-01-10


Biological activity, chemical profiling and molecular docking of tissue extracts of the sea snail Trochus erithreus

Khaled M. Zayed, Mosad A. Ghareeb, Mohamed R. Habib, Hanaa M. Abu El-Einin, Rasha E.M. Ali [...]
Graphical Abstract

Research Article     |    2023-01-17


Influence of hesperetin on the pharmacokinetics of diltiazem in rats

Ravindra Babu Pingili, Surya Sandeep Mullapudi, Sridhar Vemulapalli, Naveen Babu Kilaru
Graphical Abstract

Research Article     |    2023-01-19


Combretum hypopilinum exhibited anti-inflammatory activity in LPS-stimulated RAW 264.7 murine macrophages through inhibition of inflammatory mediators and apoptosis

Kokou Idoh, Kossivi Dosseh, Mrinmoy Gautam, Tchazou Kpatcha, Natarajan Manikandan [...]
Graphical Abstract

Research Article     |    2023-01-27


Cytotoxicity and fragmentation pattern of Datura metel L. leaves using ultra-performance liquid chromatography-mass spectroscopy

Mohammad Adam Mustapa, Muhammad Taupik, A. Muthi Andi Suryadi, Mahdalena Sy Pakaya, Julyanty Akuba [...]
Graphical Abstract

Research Article     |    2023-02-08


Assessment of health-related quality of life and its contributing factors using the WHOQOL-BREF questionnaire in patients with chronic liver disease

Manjacheri Kuppadakath Sagara, Vineesha Gangadharan, Ranjith Sristhi, Bipin Shaji, Adithi Kellarai [...]
Graphical Abstract

Research Article     |    2023-02-08


Exopolysaccharide from the mice ovarian bacterium Bacillus velezensis OM03 triggers caspase-3-dependent apoptosis in ovarian cancer cells

Sreejesh Pilakkavil Chirakkara, Asha Abraham

Graphical Abstract

Research Article     |    2023-02-08


Secondary metabolite of Aspergillus oryzae impairs cell envelope integrity Klebsiella pneumoniae producing extended-spectrum beta-lactamase

Lailia Nur Rachma, Loeki Enggar Fitri, Sumarno Reto Prawiro, Tri Yudani Mardining Raras

Graphical Abstract

Research Article     |    2023-02-08


Diuretics misuse: A cross-sectional study to explore community pharmacist’s perceptions of diuretics use and misuse

Khawla Dhamen Al-Hamaideh, Isra Mahmoud Dmour

Graphical Abstract

Research Article     |    2023-02-08


The beneficial effect of the ethanolic extract Etlingera elatior fruit on IL-1ß and caspase-3 levels in sepsis model mice

Evi Nurhayatun, Bambang Purwanto, Soetrisno Soetrisno, Dono Indarto, Eti Poncorini [...]
Graphical Abstract

Research Article     |    2023-02-08


Ethyl acetate crude fraction of Macaranga subpeltata and silymarin increase Vero cell survival and HepG2 cell death due to oxidative stress

Harto Widodo, Abdul Rohman
Graphical Abstract

Research Article     |    2023-02-25


Neuroprotective impacts of chrysin against clonazepam induced cognitive deficits in male rats

Hend A. Sabry, Mai M. Zahra, Shimaa A. Haredy, Amany S. Amer

Graphical Abstract

Research Article     |    2023-02-25


Job skill assessment of pharmacy students in South Karnataka: A cross-sectional study

Shanthi Lysetty, Anup Naha, Usha Yogendra Nayak, Virendra S. Ligade, Bhavana B. Bhat [...]
Graphical Abstract

Research Article     |    2023-02-25


Antiproliferative, proapoptotic, and antimigration activities of marine sponges against human colon cancer cell line (HCT116)

Aileen May G. Ang, Sharon Rose M. Tabugo, Mylene M. Uy

Graphical Abstract

Research Article     |    2023-02-25


Beneficial effects of Insulin and Rivastigmine in Type-3 Diabetes mellitus in rats

Abhilasha Ahlawat, Vaibhav Walia, Munish Garg
Graphical Abstract

Research Article     |    2023-02-25


Antiphotoaging effects of liposomal encapsulated superoxide dismutase extract of Bacillus altitudinis on ultraviolet-A-irradiated New Zealand rabbits’ back skin

Nurfitriyawatie Nurfitriyawatie, Ana Indrayati, Rizal Maarif Rukmana, Sari Haryanti

Graphical Abstract

Research Article     |    2023-03-04


A validated LC-MS/MS method for simultaneous quantification of antitubercular drugs in rat plasma and its application for a pharmacokinetic interaction study with Immusante®

Lakavalli Mohankumar Sharath Kumar, Mohammed Mukhram Azeemuddin, Krishna Chaitanya Routhu, Keerthi Priya, Uddagiri Venkanna Babu [...]
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Research Article     |    2023-03-04


Development and characterization of chronotherapeutic tablets of sacubitril-valsartan supramolecular complex using hupu gum and lannea gum by compression coating

Rajeswari Aleti, Kolapalli Venkata Ramana Murthy

Graphical Abstract

Research Article     |    2023-03-04


GC-MS metabolomic approach to study antimicrobial activity of the marine sponge-derived fungi Trichoderma reesei TV221

Putu Oka Samirana, Yosi Bayu Murti, Riris Istighfari Jenie, Erna Prawita Setyowati
Graphical Abstract

Research Article     |    2023-03-04


Biocompatible osimertinib nanoliposomes coated with PEGylated hyaluronic acid enhanced tumor selectivity and cytotoxicity via CD44-mediated NSCLC targeting: Development, characterization and in-vitro biochemical studies

Sanjay Kumar Kuna, Asha Deepti Choppala
Graphical Abstract

Research Article     |    2023-03-17


Pre-clinical studies of Siddha formulations advocated for anaemia: A systematic review and meta-analysis

Arumugam Rajendra Kumar, Gayathri Gunalan, Khaja Hussain Hina Firdouse, Arivazhagan Archana
Graphical Abstract

Research Article     |    2023-04-05


Antibacterial and cytotoxic secondary metabolites from endophytic fungi associated with Antidesma bunius leaves

Ni Putu Ariantari, I Putu Yogi Astara Putra, Ni Putu Eka Leliqia, Putu Sanna Yustiantara, Meitini Wahyuni Proborini [...]
Graphical Abstract

Research Article     |    2023-04-05


Computational approach to determine the combination of polyherbs based on the interaction of their metal complexes on the mucoadhesive properties of type II mucin

Eka Diyah Putri Lestari, Sri Widyarti, Djoko Herry Santjojo, Nashi Widodo, Sutiman Bambang Sumitro [...]
Graphical Abstract

Research Article     |    2023-04-05


A sensitive direct chiral liquid chromatography tandem mass spectrometry method for the enantio—Selective analysis of imeglimin in formulation

Sangamithra Ramalingam, Meyyanathan Nainar Subramania, Babu Basuvan, Ramesh Jaganathan, Anandha Jothi Dhavamani [...]
Graphical Abstract

Research Article     |    2023-04-05


Antitrypanosomal potential of the red sea soft coral Nephthea mollis supported by metabolomics profiling and molecular docking studies

Khaled M. Allam, Yaser A. Mostafa, Usama R. Abdelmohsen, Amgad I.M. Khedr, Ahmed E. Allam [...]
Graphical Abstract

Research Article     |    2023-04-15


Pharmacokinetic interaction of rosuvastatin with artichoke (Cynara scolymus L.) leaf extract in rats

Ahmad M. Al Masalmeh, Eyad Mallah, Kenza Mansoor, Luay Abu-Qatouseh, Feras Darwish El-Hajji [...]
Graphical Abstract

Research Article     |    2023-04-29


In vitro antidiabetic and advanced glycation end products inhibitory activity of methanol extracts of various Dendrobium species

Thaniwan Cheun-Arom, Boonchoo Sritularak
Graphical Abstract

Research Article     |    2023-04-29


Human platelet lysate-derived exosomes are superior to the lysate at increasing collagen deposition in a rat model of intrinsic aging

Ervina Rosmarwati, Endra Yustin Ellistasari, Arie Kusumawardani, Indah Julianto, Suci Widhiati [...]
Graphical Abstract

Research Article     |    2023-04-29


Microwave-assisted extraction of polyphenols from Eleutherine bulbosa Mill. Urb. bulbs using choline chloride-sorbitol based natural deep eutectic solvent

Laode Rijai, Selvi Tri Tang, Mukti Priastomo , Siska Siska, Niken Indriyanti [...]
Graphical Abstract

Research Article     |    2023-04-29


Pluronic® P123-coated liposomal codelivery of paclitaxel and lapatinib enhances therapeutic potential via tumor cell targeting and overcoming multidrug resistance in triple-negative breast cancer cells

Suvendu Kumar Sahoo, Subrahmanyam Pitchika
Graphical Abstract

Research Article     |    2023-05-17


Use of medicines in neonate and infants: A report of mothers’ practices

Ufuoma Shalom Ahwinahwi, Valentine Uche Odili, Magdalene Odunvbun, Anthony Ifeanyi Okeke, Uche Everister Soeze [...]
Graphical Abstract

Research Article     |    2023-05-17


GC-MS validation of the organic ionic impurity tetra-n-butylammonium bromide in Teneligliptin

Murugan Maniavannan, Paramasivam Parthiban, Palaniappan Ilayaraja, Jagatheesan Rathinavel
Graphical Abstract

Research Article     |    2023-05-18


The medicinal potential of plants from the Adenostemma genus

Nurlela Nurlela, Badrunanto, Auliya Ilmiawati, Waras Nurcholis, Hiroshi Takemori [...]
Graphical Abstract

Review Article     |    2023-01-27


Level of antibiotic contamination in the major river systems: A review on South Asian countries perspective

Prabhjot Singh Jassal, Dapinder Kaur, Manpreet Kaur, Pallavi, Disha Sharma [...]
Graphical Abstract

Review Article     |    2023-02-25


Functionalized carbon nanotubes—A boon in treating brain diseases

Rajkumar Ghosh, Jagabandhu Bag, Aparna Datta, Arup Pramanick, Isa Hassan Abubakar [...]
Graphical Abstract

Review Article     |    2023-02-25


The potential of Macaranga plants as skincare cosmetic ingredients: A review

Enih Rosamah, Muhammad Taufiq Haqiqi, Agmi Sinta Putri, Harlinda Kuspradini, Irawan Wijaya Kusuma [...]
Graphical Abstract

Review Article     |    2023-02-25


Determinants of dispensing antibiotics without prescription by community pharmacists in developing countries: A review

Teressa Andrea Esteves, Gabriel Jay Atabay, Elizabeth Yu Tan
Graphical Abstract

Review Article     |    2023-02-25


The potential effects of isoflavones on nuclear receptor modulation in bone remodeling: A review

Haryati Ahmad Hairi, Nor Hidayah Mustafa, Putri Ayu Jayusman, Ahmad Nazrun Shuid
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Review Article     |    2023-02-25


Nuclear receptors and other molecular targets in type 2 diabetes mellitus

Deepa Sugumar, Emdormi Rymbai, Soumya Vasu, Divakar Selvaraj

Graphical Abstract

Review Article     |    2023-02-25


The in-silico potential of Andrographis paniculata phytocompounds as antiviral for the treatment of COVID-19: A systematic review

Shafa Shavira, Septi Handayani, Fatmaria Fatmaria
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Review Article     |    2023-04-04


A systematic review of medicinal plants and compounds for restoring pancreatic β-cell mass and function in the management of diabetes mellitus

Neha Deora, Krishnan Venkataraman
Graphical Abstract

Review Article     |    2023-04-04


Databases and web resources for neglected tropical disease research

Praffulla Kumar Arya, Krishnendu Barik, Ajay Kumar Singh, Anil Kumar
Graphical Abstract

Review Article     |    2023-05-01


Lactic acid bacteria fermented foods: Impact on immune system and consequences over type 2 diabetes mellitus

Rahnuma Ahmad, Angus Nnamdi Oli, Ayukafangha Etando, Paras Sharma, Susmita Sinha [...]
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Review Article     |    2023-05-20


Bibliometric analysis and visualization of research on nanotechnology in dentistry from 1999 to 2022

Namrata Dagli, Bhavin Patel, Rushabh Dagli, Nihad Adnan, Rahnuma Ahmad [...]
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Short Communication     |    2023-02-08


In vitro study: Catechins as depigmenting agents inhibit melanogenesis on B16F0 cells

Widyastuti Widyastuti, Deddi Prima Putra, Satya Wydya Yenny, Aisyah Elliyanti

Graphical Abstract

Case Report     |    2023-05-20


An autopsy report of rare purulent pericarditis caused by Streptococcus anginosus infection that spread from the liver abscess

Nadiawati Abdul Razak, Siti Asma’ Mohd Saman, Rahnuma Ahmad, Mainul Haque

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Review Article     |    2023-05-04


A comprehensive review of the ethnobotanical, phytochemical, and pharmacological properties of the genus Bambusa

Mohammad Amil Zulhilmi Benjamin, Fiffy Hanisdah Saikim, Shean Yeaw Ng, Nor Azizun Rusdi
Graphical Abstract

Review Article     |    2023-05-04


Emerging corticosteroid resistance: Need for customized medication based on pharmacogenomics profiling

Navakanth Raju Ramayanam, Rajeshan Nanda Amarnath, Mohan Kumar Ramasamy, Thangavel Mahalingam Vijayakumar
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Review Article     |    2023-05-04


Assessing the potential of gastroretentive technology for gastric cancer targeting

Swati Saini, Jatin Chhabra, Archana Sharma, Manish Kumar, Inderbir Singh [...]
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Review Article     |    2023-05-04


Adverse events associated with COVID-19 treatment and their possible relationship with patient characteristics: A narrative review

Omar Yahya Al-Shargi, Samah Mukhlef Alzaid, Bodoor Saud Al-Dosari, Abeer Saad Alzubaidi
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Review Article     |    2023-05-04


Mechanism of action of Indonesian medicinal plants in inhibiting 3T3-L1 adipocyte differentiation: A review

Eko Fuji Ariyanto, Farhan Wirajati, Putri Halleyana Rahman, Afiat Berbudi, Enny Rohmawaty [...]
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Mini Review     |    2023-05-04


Pomolic acid: A short review on its chemistry, plant sources, pharmacological properties, and patents

Eric Wei Chiang Chan, Ying Ki Ng, Carine Shu Shien Lim, Vania Septa Anggraeni, Zhi Zhou Siew [...]
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Research Article     |    2023-05-04


Impact of generics competition on prices and utilization of antiepileptic medicines in Bulgaria

Manoela Manova, Zornitsa Emilova Mitkova, Alexandra Savova, Anna Borisova, Lily Peikova [...]
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Research Article     |    2023-04-08


Antimicrobial and antitubercular activity of novel pyrazole-4-carboxamide derivatives: Synthesis and characterization

C. Asha Deepthi, J. Prathyusha
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Research Article     |    2023-05-04


Neonatal outcomes associated with antimicrobial resistance: A retrospective cross-sectional study

Prashant Chandra, Faiza Iqbal, Mazhuvancherry Kesavan Unnikrisnan, Purkayastha Jayashree, Padmaja A. Shenoy [...]
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Research Article     |    2023-05-04


AQbD-based stability indicating development and validation of azilsartan medoxomil and cilnidipine by UPLC method

Swarupa Bandi, Sreedevi Adikay
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Research Article     |    2023-05-04


Simpor leaf extract (Dillenia suffruticosa Martelli) induced apoptosis of the MCF-7 and HepG2 cell lines

Sri Rahayu, Jungshan Chang, Atin Supiyani, Arief Prasetiyo

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Research Article     |    2023-05-04


Isolation of winged bean (Psophocarpus tetragonolobus L.) allergen protein to create skin prick test reagent

Lusiana Lusiana, Fransiska Rungkat Zakaria, Endang Prangdimurti, Hendra Wijaya
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Research Article     |    2023-05-04


Effect of turmeric (Curcuma longa) extract administration on tumor necrosis factor-alpha and type 1 collagen expression in UVB-light radiated BALB/c mice

Aletheia Threskeia, Willy Sandhika, Retno Pudji Rahayu

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Research Article     |    2023-05-04


Evaluation of physicochemical and antimicrobial properties of creams formulated using Pterocarpus santalinoides seeds methanol extract

Sinodukoo Eziuzo Okafo, Clement Oliseloke Anie, Christian Arerusuoghene Alalor, Lawrence Uchenna Nwankwo

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Research Article     |    2023-05-04


Metabolites analysis of the marine sponge Callyspongia affinis from Kangean Island as a potential source for anticancer candidates

Moh Farid Rahman, Aulanni, Masruri, Akhmad Sabarudin, Siti Mariyah Ulfa [...]
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Research Article     |    2023-05-04


Identification and characterization of bacteria isolated from blood cultures at KAUH in Irbid, Jordan

Nid’a Alshraiedeh, Majd Alzedan, Rawan Alsharedeh, Rasha Bani-Salameh, Majed Masadeh [...]
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Research Article     |    2023-05-04


Isorhamnetin decreased the expression of HMG-CoA reductase and increased LDL receptors in HepG2 cells

Randa El-Rayyes, Manal M. Abbas, Razan Obeidat, Manal A. Abbas
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Research Article     |    2023-05-04


Phytochemical analysis, antiproliferative and apoptosis-inducing properties of Persicaria strigosa Nakai

Ananta Swargiary, Mritunjoy Kumar Roy, Harmonjit Boro, Akalesh Kumar Verma, Manita Daimari [...]
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Research Article     |    2023-05-04


Amino acid profiling in wild Chamaenerion angustifolium populations applying chemometric analysis

Kateryna Uminska, Zigmantas Gudžinskas, Liudas Ivanauskas, Victoriya Georgiyants, Alla Kozurak [...]
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Research Article     |    2023-05-04


The potential of Clausena lansium (Lour.) peel extract consumption on hyperglycemia, hyperlipidemia and augmented oxidative stress in type-2 diabetic model rats

Wathita Phachonpai, Prathakphong Riyamongkol, Dej Mann, Terdthai Tongun

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Research Article     |    2023-05-04


Alpha-glucosidase inhibitory activity of the combination of Caesalpinia sappan L. and Garcinia mangostana extract

Nina Artanti, Indah Dwiatmi Dewijanti, Dian Muzdalifah, Anjar Windarsih, Suratno Suratno [...]
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Research Article     |    2023-05-04


Stability indicating UPLC-MS/MS method for quantification and identification of cefepime and its degradants in API

Jabeen, Bangalore Venkatappa Suma

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Research Article     |    2023-05-04


Hibiscus sabdariffa tea improved the maximum oxygen uptake (VO2max) and blood pressure in normotensive participants

Syamsul Rahmat, Annisa Alpiani, Sri Adi Sumiwi, Leonardo Lubis, Jutti Levita [...]
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Research Article     |    2023-05-04


Optimization of Graptophyllum pictum leaves extraction using a simplex centroid design focused on extracting flavonoids with antioxidant activity

Feda Anisah Makkiyah, Eldiza Puji Rahmi, Tiwuk Susantiningsih, Nelly Marliani, Rini Anggi Arista [...]
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Retraction     |    2023-05-04


Retraction of ‘Enhancing the yield of antitubercular compounds from fenugreek [Trigonella foenum-graecum (Methi)] seeds using response surface methodology'

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Research Article     |    2022-07-31


Microbial adaptations at higher altitude for sustainable development: A review

Manali Singh, Kuldeep Jayant, Dipti Singh, Deep Chandra Suyal, Abhirup Mitra [...]
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Research Article     |    2023-01-10


Computational simulations of microalgae-derived bioactive compounds as a novel inhibitor against B-Raf V600E-driven melanoma

Fiddy Semba Prasetiya, Wanda Destiarani, Irene Retno Cahya Prihastaningtyas, Mochamad Untung Kurnia Agung, Muhammad Yusuf [...]
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Research Article     |    2023-01-10


Formulation and development of novel probiotic-loaded gel for the treatment of caffeine-induced anxiety

Pooja Verma, Rohit Dutt, Siraj Anwar
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Research Article     |    2023-01-10


Cytotoxic and antioxidant activities of flavonoids and diterpenoids from Macaranga involucrata (Roxb.) Baill

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Research Article     |    2023-05-04


Simpor leaf extract (Dillenia suffruticosa Martelli) induced apoptosis of the MCF-7 and HepG2 cell lines

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Review Article     |    2023-05-04


A comprehensive review of the ethnobotanical, phytochemical, and pharmacological properties of the genus Bambusa

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Biological potency of actinomycetes extracts from rhizosphere soil of Dacrycarpus imbricatus from Toba Samosir, North Sumatra

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Emerging corticosteroid resistance: Need for customized medication based on pharmacogenomics profiling

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Antioxidant and antimicrobial activity of flowers of Wendlandia thyrsoidea, Olea dioica, Lagerstroemia speciosa and Bombax malabaricum

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Design of dissolution media for in-vitro bioequivalence testing of Lamivudine

Nagiat T Hwisa, Shanta Kumari Adiki, Prakash Katakam, Babu Rao Chandu
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Antifungal Activity of extracts from two Ouratea species on Candida albicans

Marcelo Francisco de Araújo, Francisco Eduardo Aragão Catunda Júnior, M. Gabriela Alvarez, Edgardo N. Durantini, Mário Geraldo de Carvalho [...]
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Block Copolymer Self-assembled and Cross-linked Nanoassemblies for Combination Delivery of Iron Oxide and Doxorubicin

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Antimicrobial Activity of Different Aqueous Lemon Extracts

Nada Khazal Kadhim Hindi and Zainab Adil Ghani Chabuck

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