A deep dive into the development of complex generics: A comprehensive review

Amatha Sreedevi, Prashant B. Musmade, Krishnamurthy Bhat, Sreedhar Dharmagadda, Manthan D. Janodia, Bhavana B. Bhat, Virendra S. Ligade

DOI: 10.7324/JAPS.2024.204337Pages: 001-014

Cephalosporin C acylase: Important role, obstacles, and strategies to optimize expression in E. coli

Muthi’ah Rasyidah, Sismindari Sismindari, Purwanto Purwanto

DOI: 10.7324/JAPS.2024.179954Pages: 015-024

Constituents of carbazole alkaloids and anti-cancer properties of extracts, mahanine, isomahanine, mahanimbine, and girinimbine from Bergera koenigii

Eric Wei Chiang Chan, Siu Kuin Wong

DOI: 10.7324/JAPS.2024.192931Pages: 025-034

Shedding light on Paraconiothyrium brasiliense: Secondary metabolites, biological activities, and computational studies

Sabrin R. M. Ibrahim, Abdulrahim A. Alzain, Fatima A. Elbadwi, Abdulrahman E. Koshak, Aram Hamad AlSaedi, Ahmed Ashour, Wadah Osman, Ikhlas A. Sindi, Selwan M. El-Sayed, Abdelbasset A. Farahat, Ahmed H.E. Hassan, Gamal A. Mohamed

DOI: 10.7324/JAPS.2024.184503Pages: 035-052

Empirical antibiotics versus definitive antibiotics for Sepsis patients in Indonesia: A cost-effectiveness analysis

Rini Noviyani, Khanh N. C. Duong, Nhi T. N. Ngo, Sanjeewa Kularatna, Agata Widatama, I Gusti Ayu Made Srinadi

DOI: 10.7324/JAPS.2024.195834Pages: 053-059

The trend of publication about Lumbricus rubellus for periodontitis treatment in the Scopus database: A bibliometric analysis

Lelly Andayasari, Sagung Agung Putri Dwiastuti, I Gusti Agung Ayu Dharmawati, I Putu Suiraoka, Heri Setiyo Bekti, I Gusti Agung Ayu Putu Swastini, Nurhayati, Novia Susianti, Iin Nurlinawati, Made Ayu Lely Suratri, Harimat Hendarwan, Putu Sanna Yustiantara, Eka Indra Setyawan

DOI: 10.7324/JAPS.2024.179572Pages: 060-068

Availability, prices, and affordability of essential medicines in Asia: A systematic review

Muhammad Qowiyul Amin, Susi Ari Kristina, Satibi Satibi

DOI: 10.7324/JAPS.2024.183688Pages: 069-076

Flux dynamics of C-5 amino acid precursors in fed-batch cultures of Streptomyces clavuligerus during clavulanic acid biosynthesis

Luisa María Gómez-Gaona, Howard Ramírez-Malule, David Gómez-Ríos

DOI: 10.7324/JAPS.2024.191319Pages: 077-087

Suppression of adipogenesis and stimulation of lipolysis by oxyresveratrol and heartwood extract from Artocarpus lacucha in adipocyte culture

Kanittaporn Trisat, Nanteetip Limpeanchob

DOI: 10.7324/JAPS.2024.188627Pages: 088-094

Neuroprotective effects of γ-Aminobutyric acid-enriched germinated riceberry extract in cerebral ischemic reperfusion-induced cognitive impairment mice

Payungsak Tantipaiboonwong, Komsak Pintha, Napapan Kangwan, Dej Mann, Prathakphong Riyamongkhol, Watcharaporn Preedapirom Jeefoo

DOI: 10.7324/JAPS.2024.175285Pages: 095-104

Neuroprotective effects of safinamide against autophagy in 6-hydroxydopamine-induced SH-SY5Y cell model of Parkinson’s disease

Yvonne Wei Ping Yeo, Brianna, Yiing Jye Yap, Khuen Yen Ng, Soi Moi Chye, Anna Pick Kiong Ling, Yin Yin Ooi, Yee Lian Tiong, Rhun Yian Koh

DOI: 10.7324/JAPS.2024.142043Pages: 105-112

Exploring the efficacy of the wild mushroom Astraeus hygrometricus extract on lipid profiles, insulin resistance, and oxidative stress in rats fed a high-fat diet

Wathita Phachonpai, Prathakphong Riyamongkol, Dej Mann, Nattakorn Kamkaew

DOI: 10.7324/JAPS.2024.182575Pages: 113-120

Screening of surfactant mixture ratio for preparation of oil-in-water nanoemulsion: A technical note

Shobhit Kumar, Karan Wadhwa, Rakesh Pahwa, Javed Ali, Sanjula Baboota

DOI: 10.7324/JAPS.2024.180648Pages: 121-127

Determination of phytochemical markers andrographolide, eugenol and zingerone in nilavembu kudineer by RP-HPLC method

B. Sivagami, B. Sailaja

DOI: 10.7324/JAPS.2024.180359Pages: 128-134

The effects of combined co-expression of groel/es and trigger factor chaperone towards Thermus thermophilus DNA polymerase enzyme expression on Escherichia coli BL21(DE3)

Iman Permana Maksum, Diandra Firdiani Utami, Sriwidodo Sriwidodo, Ryan Adibagus Haryanto, Riyona Desvy Pratiwi

DOI: 10.7324/JAPS.2024.152923Pages: 135-140

Ameliorative effect of Vitis gracilis leaf decoction against sensory and motoric disorders, oxidative stress, and cerebellar degeneration in diabetic mice

Putra Santoso, Alfi Yuniarti, Rita Maliza, Alimuddin Tofrizal, Dinda Fadhila Belahusna

DOI: 10.7324/JAPS.2024.174900Pages: 141-151

Phytochemical analysis and in vitro investigation of wound healing, cytotoxicity, and inflammatory response in potentially active extracts of Anogeissus dhofarica

Duaa Abuarqoub, Walid Aburayyan, Luay Rashan, Wael Abu Dayyih, Hisham Y. Al-Matubsi

DOI: 10.7324/JAPS.2024.174429Pages: 152-162

QSAR modeling of isoquinoline derivatives having AKR1C3 inhibitory activity: Lead optimization

Papichettypalle Gopinath, Dwivedi Ashish ranjan, Beda Durgaprasad, Karkara Bidhuhusan, Pathuri Raghuveer, Godela RamReddy, Kasula Ramalingeswara Rao, Dontireddy Ravisankara Reddy, Sibala Subramanyam

DOI: 10.7324/JAPS.2024.160453Pages: 163-174

SNEDDS to improve the bioactivities of Pandanus tectorius leaves: Optimization, antioxidant, and anticancer activities via apoptosis induction in human cervical cancer cell line

Alifa Husnun Kholieqoh, Murni Nur Islamiah Kassim, Tengku Sifzizul Tengku Muhammad, Khairul Anam, Yeong Yik Sung, Hermansyah Amir, Husna Nugraha Praja, Yosie Andriani

DOI: 10.7324/JAPS.2024.168694Pages: 175-189

Sorafenib combination with imatinib enhances apoptotic and cell cycle arrest effects with no effect on viability and BCR-ABL expression of K-562 cells

Belal A. Al-Husein, Ahmad Al-Azayzih, Fatema S. Redha

DOI: 10.7324/JAPS.2024.161424Pages: 190-195

Development and validation of a new LC-MS/MS method for the determination of orlistat in biological matrices using experimental design

Rubina Kauser, Sunil Kumar Chaitanya Padavala, Venkatesan Palanivel

DOI: 10.7324/JAPS.2024.191461Pages: 196-204

Scientific landscape of melatonin, its hybrids, and its derivatives as anti-tumor agents: A bibliometric analysis

Andres F. Yepes, Wilson Cardona Galeano, Howard Ramírez-Malule

DOI: 10.7324/JAPS.2024.169632Pages: 205-218

In silico modeling, formulation, optimization, and in-vitro evaluation of candidone microsponges for the management of colorectal cancer

Neha Yadav, Rohitas Deshmukh

DOI: 10.7324/JAPS.2024.1706009587Pages: 219-228