Multitargeted therapy in the convergence era: Systems pharmacology, smart delivery, and the rise of pan-biomarkers

Munikumar Manne

DOI: 10.7324/JAPS.2025.v15.i11.1EDPages: 001-007

Therapeutic potential of Cissus quadrangularis Linn. (Veldt grape) in osteoporosis and arthritis: A scoping review of preclinical evidence

Poojitha Sri Sai Parinam, Radhika Prashant Hedaoo, Mansi Patil, Anuja Mohile, Nalini Khatwani, Archana Aainapure

DOI: 10.7324/JAPS.2025.247119Pages: 008-020

Synthesis of flavonoid derivatives as anti-rheumatoid arthritis agent: A systematic literature review and meta-analyses

Andy Eko Wibowo, Ratna Asmah Susidarti, Ika Puspitasari, Sabtanti Harimurti

DOI: 10.7324/JAPS.2025.240756Pages: 021-038

In silico drug repurposing in non-small cell lung cancer by docking and molecular dynamic simulations for epidermal growth factor receptor allosteric site inhibition

Swastika Maity, Megh Pravin Vithalkar, Krishnaprasad Baby, Usha Yogendra Nayak, Karkala Sreedhara Ranganath Pai, Yogendra Nayak

DOI: 10.7324/JAPS.2025.242311Pages: 039-049

Oxyresveratrol derived from Artocarpus lakoocha extract represents a potential natural agent for treating acne and skin inflammation

Nalin Wongkattiya, Phanchana Sanguansermsri, Ian Fraser, Aussavashai Shuayprom, Sirada Pongmuangmul, Rames Koranee, Pornnapa Khampan, Donruedee Sanguansermsri

DOI: 10.7324/JAPS.2025.v15.i11.5Pages: 050-057

Downregulation of Cyclin-D, Wnt3a, and C-Myc in prostate cancer by dose-dependent combination of concentrated marine minerals and curcumin

Syafika Alaydrus, Sriwidodo Sriwidodo, Ajeng Diantini, Riezki Amalia, Wahyuni Wahyuni, Ayu Wulandari

DOI: 10.7324/JAPS.2025.217025Pages: 058-066

Evaluation of attenuative potential of flaxseeds in high-calorie, high-fat, and fructose-induced metabolic syndrome indicators in Wistar rats without dietary reversal

Babi Dutta, Archana Parampalli Raghavendra, Aparna Tripathy, Deepak Nayak Manel, Shashikiran Umakanth, Shobha U. Kamath

DOI: 10.7324/JAPS.2025.219097Pages: 067-088

Application of microwave-assisted extraction using glucose-citric acid deep eutectic solvent for enhancement of polyphenols extraction from Peperomia pellucida (L) Kunth herb

Islamudin Ahmad, Baso Didik Hikmawan, Lizma Febrina, Junaidin Junaidin, Arman Rusman, Supriatno Salam, Eko Suhartono, Yusanto Nugroho, Iskandar Iskandar, Mufrida Zein, Veri Julianto, Oky Rahmanto, Abdul Mun’im

DOI: 10.7324/JAPS.2025.231184Pages: 089-097

Therapeutic effects of Bajakah kalalawit extract (Uncaria gambir Roxb.) in HCl/ethanol-induced rats as an animal model in acute gastritis: UHPLC MS/MS profiling and in vivo approach with in silico validation

Aulia Andi Mustika, Lina Noviyanti Sutardi, Andriyanto Andriyanto, Sharon Aurellia, Anisa Rahma, Rahayu Woro Wiranti, Andhika Yudha Prawira, Derajat Taruno Jati, Ekowati Handharyani, Setyanto Tri Wahyudi

DOI: 10.7324/JAPS.2025.231503Pages: 098-113

Evaluation of depression training program for community pharmacists in Indonesia: A quasi-experimental study

Nisa Febrinasari, Anna Wahyuni Widayanti, Yayi Suryo Prabandari, Satibi Satibi

DOI: 10.7324/JAPS.2025.233756Pages: 114-122

Development of Bergamot nanoemulgel using central composite design and its evaluation for antimicrobial activity

Koushik Yetukuri, Marakanam Srinivasan Umashankar, S.T.V. Raghavamma

DOI: 10.7324/JAPS.2025.236869Pages: 123-135

Exploring flavonoids as multi-target therapeutic agents in Alzheimer’s disease: Insights from Network Pharmacology, Molecular Docking, and Dynamics

Logeshwari Bala, Srikanth Jeyabalan, Gayathri Veeraraghavan, Krishnaraj Kaliaperumal, Chetan Ashok, Devaraja Dravida Pandiyan

DOI: 10.7324/JAPS.2025.v15.i11.12Pages: 136-153

Comparative efficacy of Syzygium cumini leaf extract and chemical disinfectants against hospital floor isolates: First report of benzalkonium chloride-resistant Mucor sp.

Haorongbam Joldy Devi, Prathiba Gnanasekaran, Yumnam Asha Devi, Durai Saravanan, Thiyagarajan Gopal, Venkataraman Balakumar, Priya Sathish, Kavitha Nataraja, Blessing Kailas Jeya Sundar, Fidelis Daflin Femi

DOI: 10.7324/JAPS.2025.v15.i11.13Pages: 154-168