Effect of ginger (Zingiber officinale R.) on metiram-inhibited spermatogenesis and induced apoptosis in albino mice
Saber A. Sakr, Gamal M. Badawy
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The enlargements of liver size induced by orotic acid and di (2-ethyl hexyl) phthalate occur in different metabolic pathways
Yohanes Buang
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Withaferin A targets apoptosis inhibitor cIAP1: A potential anticancer candidate
V.P. Wadegaonkar, P.A. Wadegaonkar
DOI: 10.7324/JAPS.2012.2527Pages: 154-157
Cytotoxic and Apoptotic Effect of Commercial Tinctures of Scutellaria baicalensis on Lung Cancer Cell Lines
Mbagwu IS, Ilodigwe EE., Ajaghaku DL, Uzodinma SU, Osonwa UE
DOI: 10.7324/JAPS.2013.30209Pages: 052-059
Modulatory effect of Allium sativum Ethanolic Extract on Cultured Human Lymphocytes
Sukanya Shetty, Shama Rao, SuchethaKumari N, Madhu L N, Vishakh R
DOI: 10.7324/JAPS.2013.3413Pages: 073-077
In silico Analysis of 3D-QSAR and Molecular Docking for Bcl-2 Inhibitors to Potential Anticancer Drug Development
Ramachandran M, Balwin Nambikkairaj, Kumaran K, Arun Kumar De and G.Ramesh Kumar
DOI: 10.7324/JAPS.2013.31005Pages: 023-029
In vitro cytotoxicity effects of single and combination Nigella sativa and Zingiber zerumbet extracts on human myeloid leukemia (HL60) cells and its mode of cell death
Norfazlina M.N., Farida Zuraina M.Y., Rajab N.F, Mohd Nazip S., Rumiza A.R., Suziana Zaila C.F., Lek Mun L., Nurshahirah N., Florinsiah L.
DOI: 10.7324/JAPS.2014.40509Pages: 051-055
Cytotoxic activity and apoptosis induction of 8-hydroxyisocapnolactone-2´,3´-diol and its combination with Doxorubicin on MCF-7 and T47D cells
Ratna Asmah Susidarti, Riris Istighfari Jenie, Muthi’ Ikawati, Dyaningtyas Dewi Pamungkas Putri, Edy Meiyanto
DOI: 10.7324/JAPS.2014.40614Pages: 089-097
Evaluation of in-vitro apoptosis induction, cytotoxic activity of Hymenodictyon excelsum (Roxb) Wall in Dalton’s lymphoma ascites (DLA) and Lung fibroblast - Mouse L929 cell lines
Kalathil Khairunnisa and Dhananjayan Karthik
DOI: 10.7324/JAPS.2014.40803Pages: 011-017
Combination of Cisplatin and Cinnamon Essential Oil Inhibits HeLa Cells Proliferation through Cell Cycle Arrest
Yonika Arum Larasati, Dyaningtyas Dewi Pamungkas Putri, Rohmad Yudi Utomo, Adam Hermawan, Edy Meiyanto
DOI: 10.7324/JAPS.2014.41203Pages: 014-019
The possible protective effect of Coriandrum sativum seeds methanolic extract on hepato-renal toxicity induced by sodium arsenite in albino rats
Mostafa Saeed, Ahmed Amen, Abdelgawad Fahmi, Islam El Garawani, Sadya Sayed
DOI: 10.7324/JAPS.2014.41208Pages: 044-051
In vitro Cytotoxic Activity of New Triphenyltin (IV) Alkyl-isopropyl-di-thiocarbamate Compounds on Human Acute T-Lymphoblastic Cell Line
Normah Awang, Nor Syaidatul Akmal Mohd Yousof, Nor Fadilah Rajab, Nurul Farahana Kamaludin
DOI: 10.7324/JAPS.2015.54.S2Pages: 007-011
Cytotoxic effect and apoptotic activity of Parmentiera edulis DC. hexane extract on the breast cancer cell line MDA-MB-231
Cynthia Carolina Estanislao Gómez, Cynthia Ordaz Pichardo, Eduardo San Martín Martínez, Nury Pérez Hernández, Guillermo Pérez Ishiwara, María del Consuelo Gómez García
DOI: 10.7324/JAPS.2016.600103Pages: 015-022
Hepcidin TH1-5 Induces Apoptosis and Activate Caspase-9 in MCF-7 Cells
Mohammed Al-kassim Hassan, Wan-Atirah Azemin, Saravanan Dharmaraj, Khamsah Suryati Mohd
DOI: 10.7324/JAPS.2016.60211Pages: 081-086
Radiomodulatory Role of Psidium guajava Leaf Extracts against X-ray Induced Genotoxicity, Oxidative stress and Apoptosis in albino Wistar Rat Model
Amith Kumar, Reshma Kumarchandra, Rajalakshmi Rai, B. S. Satish Rao
DOI: 10.7324/JAPS.2016.60310Pages: 058-065
The potential therapeutic role of Fenugreek saponin against Alzheimer's disease: Evaluation of apoptotic and acetylcholinesterase inhibitory activities
Wagdy K. B. Khalil, Hanaa M. Roshdy, Salwa M. Kassem
DOI: 10.7324/JAPS.2016.60925Pages: 166-173
Assessment of immunological, haematological and biochemical status after Sofosbuvir-based combination therapy in HCV Egyptian patients from Menoufia Province
Hany M. Ibrahim, Mohammed A. Soliman, Ibrahim A. El-Elaimy, Rasha S. El-Hageen
DOI: 10.7324/JAPS.2016.601024Pages: 174-180
Extracts of Codiaeum variegatum (L.) A. Juss is Cytotoxic on Human Leukemic, Breast and Prostate Cancer Cell Lines
Mathias Tawiah Anim, Christopher Larbie, Regina Appiah-Opong, Isaac Tuffour, Kofi Baffour-Awuah Owusu, Abigail Aning
DOI: 10.7324/JAPS.2016.601114Pages: 087-093
Molecular Docking studies of Synthetic and Natural compounds against cFLIP protein in cancer
C. Nagamani, K. Devi, G. Sridharbabu, Vadlakonda Rajashekar, Sreenivas Enaganti
DOI: 10.7324/JAPS.2017.70317Pages: 109-112
Anti-oxidative and cytotoxic attributes of phenolic rich ethanol extract of Musa balbisiana Colla inflorescence
Vageesh Revadigar, Majed Ahmed Al-Mansoub, Muhammad Asif, Mohammad Razak Hamdan, Amin Malik Shah Abdul Majid, Mohd Zaini Asmawi, Vikneswaran Murugaiyah
DOI: 10.7324/JAPS.2017.70518Pages: 103-110
Ethyl acetate fraction of Calotropis gigantea roots induce apoptosis through increased G2/M and increased expression of caspase-8 in colon cancer WiDr cell line
Roihatul Mutiah, Aty widyawaruyanti, Sukardiman Sukardiman
DOI: 10.7324/JAPS.2017.70728Pages: 197-201
Evaluation on Hydnophytum formicarum Tuber from Setiu Wetland (Malaysia) and Muara Rupit (Indonesia) for Antibacterial and Antioxidant activities, and anti-cancer Potency against MCF-7 and HeLa Cells
Yosie Andriani, Habsah Mohamad, Murni Nur Islamiah Kassim, Nur Diyana Rosnan, Desy Fitrya Syamsumir, Jasnizat Saidin, Tengku Sifzizul Tengku Muhamma, Hermansyah Amir
DOI: 10.7324/JAPS.2017.70904Pages: 030-037
Diabetes mellitus-induced male reproductive impairment: The role of natural products: A review
Victor Udo Nna, Ainul Bahiyah Abu Bakar, Mahaneem Mohamed
DOI: 10.7324/JAPS.2017.70932Pages: 233-242
Induction of Apoptosis and Phase-Cell Cycle Inhibition of G0-G1, S, G2-M of T47D Breast Cancer Cells on Treatment with Ethyl Acetate Fraction of Jackfruit Parasite Leaves (Macrosolen cochinensis)
Roihatul Mutiah, Christyaji Indradmojo, Hardiyanti Helda Dwi, Tias Pramesti Griana, Anik Listyana, Ria Ramdhani
DOI: 10.7324/JAPS.2017.71020Pages: 138-143
Synthesis And Anticancer Screening Of Novel Spiro[Chroman-2,4′- Piperidin]-4-One Derivatives With Apoptosis-Inducing Activity
Shaimaa A. Abdelatef, Mohammed T. El-Saadi, Noha H. Amin, Ahmed H. Abdelazeem, Khaled R.A. Abdellatif
DOI: 10.7324/JAPS.2018.8102Pages: 009-016
CD47 is Up-Regulated on Leukaemia Cells to Avoid Apoptosis In Vitro
Ikenna Kingsley Uchendu, Oliver Chukwuma Orji, Chidozie Elochukwu Agu, Blessing Eluke Chekwube, Tochi Faith Nwosu
DOI: 10.7324/JAPS.2018.8314Pages: 099-103
Treated Plasmodium berghei infected pregnant mice by Andrographis paniculata tablet (AS201-01) decreasing the TLR-4 expression and apoptosis index of placental tissue
Budi Prasetyo, Diantri Nari Ratih, Yustinasari, Hilkatul Ilmi, Lidya Tumewu, Aty Widyawaruyanti
DOI: 10.7324/JAPS.2018.8415Pages: 105-108
Mango mistletoe Dendrophthoe pentandra leaf extract acts synergistically with 5-Fluorouracil to induce apoptosis and increase p21 expression in human cervical adenocarcinoma HeLa cells by reducing survivin expression
Agustina Tri Endharti, Eni Sulastri, Rabiah Umanailo, Yunialce, Tatit Nurseta, Kusworini Handono
DOI: 10.7324/JAPS.2018.8702Pages: 010-015
Dendrophthoe pentandra Leaves Extract Promotes Apoptotic Effects of Doxorubicin in Human Breast Cancer Cell via Modulation of Intracellular Calcium and Survivin
Agustina Tri Endharti, Tri Esti Wahyuningtyas, Hardini, Kusworini Handono, Edi Widjajanto, Sofy Permana
DOI: 10.7324/JAPS.2018.8806Pages: 039-043
ROS mediated DNA damage and induction of apoptosis in cervical cancer cells by Heliotropium indicum L.
Subhabrata Paul, Rita Kundu
DOI: 10.7324/JAPS.2018.8814Pages: 092-106
Dendrophthoe pentandra Induced Apoptosis and Cell Cycle Arrest at G1/S in Human Breast Adenocarcinoma Cells, MCF-7 via Up- Regulation of p53
Nik Aina Syazana Nik Zainuddin, Yusmazura Zakaria, Mohd Dasuki Sul’ain
DOI: 10.7324/JAPS.2018.8919Pages: 130-141
Ethyl acetate fraction of garlic (Allium sativum) inhibits the viability of MCF7 and HepG2 through induction of apoptosis and G2/M phase cell cycle arrest
Amira M. Shaban, Ola Hammouda, Laila Abou Ghazala, Mai Raslan, Mohammed A. El-Magd
DOI: 10.7324/JAPS.2018.8920Pages: 142-150
In-vitro cytotoxicity and apoptosis mechanism of ethyl acetate extract from Trichoderma reesei strain TV221 associated with marine sponge: Stylissa flabelliformis
Erna Prawita Setyowati, Sylvia Utami Tunjung Pratiwi, Purwantiningsih, Indah Purwantini
DOI: 10.7324/JAPS.2018.8921Pages: 151-157
Cytotoxic effects and anti-proliferative cancer activity of coelomic fluid from Lumbricus rubellus promotes apoptosis and reduces G2/M phase progression in HT-29 cells
Sofy Permana, Pearlindah, Zurniatus Sholihah, Agustin Iskandar, Hani Susanti, Agustina Tri Endharti
DOI: 10.7324/JAPS.2018.81104Pages: 028-034
Antiproliferative and apoptosis inducing potential of whole plant extracts of Sesuvium portulacastrum against different cancer cell lines
Sathvika Chintalapani, M. S. Swathi, Mangamoori Lakshmi Narasu
DOI: 10.7324/JAPS.2019.90205Pages: 038-043
Combined effects of celecoxib and cepharanthine on human colorectal cancer cells in vitro
Parawee Lerdwanangkun, Piyanuch Wonganan, Robin James Storer, Wacharee Limpanasithikul
DOI: 10.7324/JAPS.2019.90415Pages: 117-125
Cytotoxicity evaluation and the mode of cell death of K562 cells induced by organotin (IV) (2-methoxyethyl) methyldithiocarbamate compounds
Nurul Farahana Kamaludin, Nazifa Ismail, Normah Awang, Rapidah Mohamad, Norraphat Uttraphan Pim
DOI: 10.7324/JAPS.2019.90602Pages: 010-015
Water extract of mangosteen suppresses H2O2-induced endothelial apoptosis by inhibiting oxidative stress
Kanjana Jittiporn, Primchanien Moongkarndi, Jutima Samer, Sarawut Kumphune, Wisuda Suvitayavat
DOI: 10.7324/JAPS.2019.90902Pages: 010-016
Papain-mediated reduction of MTT is an artifact but not an indicator of cell apoptosis in Saccharomyces cerevisiae
Shafaque Asif, Gurjeet Kaur, Usha Pendurthi, Vineet Awasthi
DOI: 10.7324/JAPS.2019.90917Pages: 119-124
Chemotherapeutic effect of Ulmus pumila leaves methanolic extract against N-methyl-N-nitrosourea-induced mammary carcinoma in female rats: An in vitro and in vivo study
Amal G. Hussien, Ibrahim H. Borai, Mahmoud M. Said, Khaled Mahmoud, Mamdouh M. Ali
DOI: 10.7324/JAPS.2019.91209Pages: 057-068
Effects of progesterone and estradiol on the inflammatory and apoptotic markers of ovariectomized rats challenged with acute septic systemic inflammation
Sinan Subhi Farhan, Samir Saad Mahgoub, Saad Abdulrahman Hussain
DOI: 10.7324/JAPS.2019.91214Pages: 103-107
Antiproliferative and apoptosis effect of hyptolide from Hyptis pectinata (L.) Poit on human breast cancer cells
Meiny Suzery, Bambang Cahyono, Nur Dina Amalina
DOI: 10.7324/JAPS.2020.102001Pages: 001-006
Modulation impact of Diazinon forms on gene expression profile and DNA damage pathway in male mice
Neama I. Ali, Lamiaa M. Salem, Sawsan Y. Elateek, Wagdy K. B. Khalil
DOI: 10.7324/JAPS.2020.10808Pages: 067-074
Apoptosis on non-small lung cancer cells and DPPH radical scavenging activity of the crude ethyl acetate extract of a soil bacterial species FEAI-1
Most. Farida Khatun, Md. Uzzal Haque, Abu Syed Md Anisuzzaman, Md. Anwar Ul Islam
DOI: 10.7324/JAPS.2021.110108Pages: 078-083
Combination effect of cisplatin and gallic acid on apoptosis and antioxidant enzymes level in cervical cancer (HeLa) cells
Norlida Mamat, Hasmah Abdullah, Hermizi Hapidin, Noor Fatmawati Mokhtar
DOI: 10.7324/JAPS.2021.110310Pages: 092-099
Goniothalamus lanceolatus extract inhibits the growth of human ovarian cancer cells through migration suppression and apoptosis induction
Nasibah Razali, Norodiyah Othman, Nur Hilwani Ismail, Nur Vicky Bihud, Nor Hadiani Ismail, Farida Zuraina Mohd Yusof
DOI: 10.7324/JAPS.2021.110410Pages: 076-087
Synthesis, cytotoxicity, and promising anticancer potential of novel β-amino- and β-iminophosphonates
Vanya Koleva, Irina Yotova, Asya Dragoeva, Dobromir Enchev
DOI: 10.7324/JAPS.2021.110708Pages: 080-088
A new curcumin analog, CCA-1.1, induces cell death and cell cycle arrest in WiDr colon cancer cells via ROS generation
Febri Wulandari, Muthi Ikawati, Mitsunori Kirihata, Jun-Ya Kato, Edy Meiyanto
DOI: 10.7324/JAPS.2021.1101014Pages: 099-105
Mitochondrial pathway mediated apoptosis and cell cycle arrest triggered by cobalt(III) complex in Dalton’s lymphoma cells
Praveen Kumar Verma, Mannu Kumar Gond, Manoj Kumar Bharty, Arbind Acharya
DOI: 10.7324/JAPS.2021.1101002Pages: 007-015
Evaluation of the cytotoxic activity of Tamarix articulata and its anticancer potential in prostate cancer cells
Abdullah M. Alnuqaydan, Abdulmajeed G. Almutary, Ohoud Y. Alshehri, Hanan Ali Henidi, Abdullah M. Alajlan, Abdullah Al Tamim, Abdullah Alowaifeer, Mohd Younis Rather, Bilal Rah
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Quillaja saponaria bark saponin attenuates methotrexate induced hepatic oxidative stress, inflammation and associated liver injury in rats
Mustafa Ahmed Abdel-Reheim, Ahmed Amine Ashour, Mohamed Abdelrazik Khattab, Ahmed Gaafar A. Gaafar
DOI: 10.7324/JAPS.2022.120510Pages: 129-141
Heat shock protein-70 expression in CSCs tumor-associated macrophages induced by Typhonium flagelliforme tuber extract
Sugeng Ibrahim, Agung Putra, Nur Dina Amalina, Iqbal Pahlevi Adeputra Nasution
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Proapoptotic activity of essential oils from Syzygium aromaticum, Melaleuca cajuputi, and Cymbopogon nardus on HeLa human cervical cancer cells
Happy Kurnia Permatasari, Anita Dominique Subali, Muhammad Yusuf, Holipah Holipah
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Petroleum ether extract of Ophiorrhiza eriantha Wight induces apoptosis in human breast cancer MCF-7 cell line
Abdul Jaleel, Malarkodi Velraj
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Combretum hypopilinum exhibited anti-inflammatory activity in LPS-stimulated RAW 264.7 murine macrophages through inhibition of inflammatory mediators and apoptosis
Kokou Idoh, Kossivi Dosseh, Mrinmoy Gautam, Tchazou Kpatcha, Natarajan Manikandan, Amegnona Agbonon, Muthiah Ramanathan, Messanvi Gbeassor
DOI: 10.7324/JAPS.2023.119177Pages: 193-198
Comparative metabolite profiling of Eleutherine bulbosa ethanol and water extracts by UPLC-MS/MS and their cytotoxic effects on T47D cells
Roihatul Mutiah, Zawilatul Muzazanah, Rahmi Annisa, Ermin Rachmawati, Avin Ainur Fitrianingsih
DOI: 10.7324/JAPS.2024.176492Pages: 052-062
Anti-cancer potential of sea grape (Caulerpa racemosa) extract by altering epithelial-mesenchymal transition and pro-apoptosis proteins expression in MCF-7 breast cancer cells
Happy Kurnia Permatasari, Nasim Amar, Faqrizal Ria Qhabibi, Nur Iedha Tertiana, Anita Dominique Subali, Vincentinus Mario Yusuf, Dennis Ievan Hakim, Satrio Adi Nugroho, Wibi Riawan, Bambang Prijadi
DOI: 10.7324/JAPS.2024.169691Pages: 176-184
Anti-proliferative activity and apoptotic induction of tannins extracted from Quercus infectoria on oral cancer KB cell lines
Fazil Ahmad, Krishna Mohan Surapaneni, Abeer Mohammed Al-Subaie, Balu Kamaraj
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Africa leaf (Vernonia amygdalina Delille.) DCM extract synergistically supports growth suppression effect of doxorubicin on MCF7 and MCF7/HER2 with different effects on cell cycle progression and apoptosis evidence
Novia Permata Hapsari, Desty Restia Rahmawati, Nadzifa Nugraheni, Mila Hanifa, Denny Satria, Poppy Anjelisa Zaitun Hasibuan, Edy Meiyanto
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The combination of fraction A3 of Cyrtostachys renda Blume with doxorubicin improved cytotoxicity against T47D cell line through cell cycle arrest and apoptotic induction
Syamsurizal Syamsurizal, Diah Tri Utami
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SNEDDS to improve the bioactivities of Pandanus tectorius leaves: Optimization, antioxidant, and anticancer activities via apoptosis induction in human cervical cancer cell line
Alifa Husnun Kholieqoh, Murni Nur Islamiah Kassim, Tengku Sifzizul Tengku Muhammad, Khairul Anam, Yeong Yik Sung, Hermansyah Amir, Husna Nugraha Praja, Yosie Andriani
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Sorafenib combination with imatinib enhances apoptotic and cell cycle arrest effects with no effect on viability and BCR-ABL expression of K-562 cells
Belal A. Al-Husein, Ahmad Al-Azayzih, Fatema S. Redha
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Diterpene alcohol fraction of Cyperus rotundus Linn essential oil regulates Bcl-2 and Bax expression inducing apoptosis on HeLa in vitro and in silico
Susianti Susianti, Yanwirasti Yanwirasti, Eryati Darwin, Jamsari Jamsari, Arif Setiawansyah
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