Effect of ginger (Zingiber officinale R.) on metiram-inhibited spermatogenesis and induced apoptosis in albino mice

Saber A. Sakr, Gamal M. Badawy

Pages: 131-136

Graphical Abstract

The enlargements of liver size induced by orotic acid and di (2-ethyl hexyl) phthalate occur in different metabolic pathways

Yohanes Buang

Pages: 71-75

Graphical Abstract

Withaferin A targets apoptosis inhibitor cIAP1: A potential anticancer candidate

V.P. Wadegaonkar, P.A. Wadegaonkar

DOI: 10.7324/JAPS.2012.2527Pages: 154-157

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Modulatory effect of Allium sativum Ethanolic Extract on Cultured Human Lymphocytes

Sukanya Shetty, Shama Rao, SuchethaKumari N, Madhu L N, Vishakh R

DOI: 10.7324/JAPS.2013.3413Pages: 073-077

Graphical Abstract

In vitro cytotoxicity effects of single and combination Nigella sativa and Zingiber zerumbet extracts on human myeloid leukemia (HL60) cells and its mode of cell death

Norfazlina M.N., Farida Zuraina M.Y., Rajab N.F, Mohd Nazip S., Rumiza A.R., Suziana Zaila C.F., Lek Mun L., Nurshahirah N., Florinsiah L.

DOI: 10.7324/JAPS.2014.40509Pages: 051-055

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Cytotoxic activity and apoptosis induction of 8-hydroxyisocapnolactone-2´,3´-diol and its combination with Doxorubicin on MCF-7 and T47D cells

Ratna Asmah Susidarti, Riris Istighfari Jenie, Muthi’ Ikawati, Dyaningtyas Dewi Pamungkas Putri, Edy Meiyanto

DOI: 10.7324/JAPS.2014.40614Pages: 089-097

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Combination of Cisplatin and Cinnamon Essential Oil Inhibits HeLa Cells Proliferation through Cell Cycle Arrest

Yonika Arum Larasati, Dyaningtyas Dewi Pamungkas Putri, Rohmad Yudi Utomo, Adam Hermawan, Edy Meiyanto

DOI: 10.7324/JAPS.2014.41203Pages: 014-019

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The possible protective effect of Coriandrum sativum seeds methanolic extract on hepato-renal toxicity induced by sodium arsenite in albino rats

Mostafa Saeed, Ahmed Amen, Abdelgawad Fahmi, Islam El Garawani, Sadya Sayed

DOI: 10.7324/JAPS.2014.41208Pages: 044-051

Graphical Abstract

Cytotoxic effect and apoptotic activity of Parmentiera edulis DC. hexane extract on the breast cancer cell line MDA-MB-231

Cynthia Carolina Estanislao Gómez, Cynthia Ordaz Pichardo, Eduardo San Martín Martínez, Nury Pérez Hernández, Guillermo Pérez Ishiwara, María del Consuelo Gómez García

DOI: 10.7324/JAPS.2016.600103Pages: 015-022

Graphical Abstract

Hepcidin TH1-5 Induces Apoptosis and Activate Caspase-9 in MCF-7 Cells

Mohammed Al-kassim Hassan, Wan-Atirah Azemin, Saravanan Dharmaraj, Khamsah Suryati Mohd

DOI: 10.7324/JAPS.2016.60211Pages: 081-086

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Assessment of immunological, haematological and biochemical status after Sofosbuvir-based combination therapy in HCV Egyptian patients from Menoufia Province

Hany M. Ibrahim, Mohammed A. Soliman, Ibrahim A. El-Elaimy, Rasha S. El-Hageen

DOI: 10.7324/JAPS.2016.601024Pages: 174-180

Graphical Abstract

Extracts of Codiaeum variegatum (L.) A. Juss is Cytotoxic on Human Leukemic, Breast and Prostate Cancer Cell Lines

Mathias Tawiah Anim, Christopher Larbie, Regina Appiah-Opong, Isaac Tuffour, Kofi Baffour-Awuah Owusu, Abigail Aning

DOI: 10.7324/JAPS.2016.601114Pages: 087-093

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Ethyl acetate fraction of Calotropis gigantea roots induce apoptosis through increased G2/M and increased expression of caspase-8 in colon cancer WiDr cell line

Roihatul Mutiah, Aty widyawaruyanti, Sukardiman Sukardiman

DOI: 10.7324/JAPS.2017.70728Pages: 197-201

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Evaluation on Hydnophytum formicarum Tuber from Setiu Wetland (Malaysia) and Muara Rupit (Indonesia) for Antibacterial and Antioxidant activities, and anti-cancer Potency against MCF-7 and HeLa Cells

Yosie Andriani, Habsah Mohamad, Murni Nur Islamiah Kassim, Nur Diyana Rosnan, Desy Fitrya Syamsumir, Jasnizat Saidin, Tengku Sifzizul Tengku Muhamma, Hermansyah Amir

DOI: 10.7324/JAPS.2017.70904Pages: 030-037

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Diabetes mellitus-induced male reproductive impairment: The role of natural products: A review

Victor Udo Nna, Ainul Bahiyah Abu Bakar, Mahaneem Mohamed

DOI: 10.7324/JAPS.2017.70932Pages: 233-242

Graphical Abstract

Induction of Apoptosis and Phase-Cell Cycle Inhibition of G0-G1, S, G2-M of T47D Breast Cancer Cells on Treatment with Ethyl Acetate Fraction of Jackfruit Parasite Leaves (Macrosolen cochinensis)

Roihatul Mutiah, Christyaji Indradmojo, Hardiyanti Helda Dwi, Tias Pramesti Griana, Anik Listyana, Ria Ramdhani

DOI: 10.7324/JAPS.2017.71020Pages: 138-143

Graphical Abstract

CD47 is Up-Regulated on Leukaemia Cells to Avoid Apoptosis In Vitro

Ikenna Kingsley Uchendu, Oliver Chukwuma Orji, Chidozie Elochukwu Agu, Blessing Eluke Chekwube, Tochi Faith Nwosu

DOI: 10.7324/JAPS.2018.8314Pages: 099-103

Graphical Abstract

Treated Plasmodium berghei infected pregnant mice by Andrographis paniculata tablet (AS201-01) decreasing the TLR-4 expression and apoptosis index of placental tissue

Budi Prasetyo, Diantri Nari Ratih, Yustinasari, Hilkatul Ilmi, Lidya Tumewu, Aty Widyawaruyanti

DOI: 10.7324/JAPS.2018.8415Pages: 105-108

Graphical Abstract

Ethyl acetate fraction of garlic (Allium sativum) inhibits the viability of MCF7 and HepG2 through induction of apoptosis and G2/M phase cell cycle arrest

Amira M. Shaban, Ola Hammouda, Laila Abou Ghazala, Mai Raslan, Mohammed A. El-Magd

DOI: 10.7324/JAPS.2018.8920Pages: 142-150

Graphical Abstract

In-vitro cytotoxicity and apoptosis mechanism of ethyl acetate extract from Trichoderma reesei strain TV221 associated with marine sponge: Stylissa flabelliformis

Erna Prawita Setyowati, Sylvia Utami Tunjung Pratiwi, Purwantiningsih, Indah Purwantini

DOI: 10.7324/JAPS.2018.8921Pages: 151-157

Graphical Abstract

Antiproliferative and apoptosis inducing potential of whole plant extracts of Sesuvium portulacastrum against different cancer cell lines

Sathvika Chintalapani, M. S. Swathi, Mangamoori Lakshmi Narasu

DOI: 10.7324/JAPS.2019.90205Pages: 038-043

Graphical Abstract

Combined effects of celecoxib and cepharanthine on human colorectal cancer cells in vitro

Parawee Lerdwanangkun, Piyanuch Wonganan, Robin James Storer, Wacharee Limpanasithikul

DOI: 10.7324/JAPS.2019.90415Pages: 117-125

Graphical Abstract

Cytotoxicity evaluation and the mode of cell death of K562 cells induced by organotin (IV) (2-methoxyethyl) methyldithiocarbamate compounds

Nurul Farahana Kamaludin, Nazifa Ismail, Normah Awang, Rapidah Mohamad, Norraphat Uttraphan Pim

DOI: 10.7324/JAPS.2019.90602Pages: 010-015

Graphical Abstract

Water extract of mangosteen suppresses H2O2-induced endothelial apoptosis by inhibiting oxidative stress

Kanjana Jittiporn, Primchanien Moongkarndi, Jutima Samer, Sarawut Kumphune, Wisuda Suvitayavat

DOI: 10.7324/JAPS.2019.90902Pages: 010-016

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Papain-mediated reduction of MTT is an artifact but not an indicator of cell apoptosis in Saccharomyces cerevisiae

Shafaque Asif, Gurjeet Kaur, Usha Pendurthi, Vineet Awasthi

DOI: 10.7324/JAPS.2019.90917Pages: 119-124

Graphical Abstract

Chemotherapeutic effect of Ulmus pumila leaves methanolic extract against N-methyl-N-nitrosourea-induced mammary carcinoma in female rats: An in vitro and in vivo study

Amal G. Hussien, Ibrahim H. Borai, Mahmoud M. Said, Khaled Mahmoud, Mamdouh M. Ali

DOI: 10.7324/JAPS.2019.91209Pages: 057-068

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Effects of progesterone and estradiol on the inflammatory and apoptotic markers of ovariectomized rats challenged with acute septic systemic inflammation

Sinan Subhi Farhan, Samir Saad Mahgoub, Saad Abdulrahman Hussain

DOI: 10.7324/JAPS.2019.91214Pages: 103-107

Graphical Abstract

Antiproliferative and apoptosis effect of hyptolide from Hyptis pectinata (L.) Poit on human breast cancer cells

Meiny Suzery, Bambang Cahyono, Nur Dina Amalina

DOI: 10.7324/JAPS.2020.102001Pages: 001-006

Graphical Abstract

Modulation impact of Diazinon forms on gene expression profile and DNA damage pathway in male mice

Neama I. Ali, Lamiaa M. Salem, Sawsan Y. Elateek, Wagdy K. B. Khalil

DOI: 10.7324/JAPS.2020.10808Pages: 067-074

Graphical Abstract

Apoptosis on non-small lung cancer cells and DPPH radical scavenging activity of the crude ethyl acetate extract of a soil bacterial species FEAI-1

Most. Farida Khatun, Md. Uzzal Haque, Abu Syed Md Anisuzzaman, Md. Anwar Ul Islam

DOI: 10.7324/JAPS.2021.110108Pages: 078-083

Graphical Abstract

Combination effect of cisplatin and gallic acid on apoptosis and antioxidant enzymes level in cervical cancer (HeLa) cells

Norlida Mamat, Hasmah Abdullah, Hermizi Hapidin, Noor Fatmawati Mokhtar

DOI: 10.7324/JAPS.2021.110310Pages: 092-099

Graphical Abstract

Goniothalamus lanceolatus extract inhibits the growth of human ovarian cancer cells through migration suppression and apoptosis induction

Nasibah Razali, Norodiyah Othman, Nur Hilwani Ismail, Nur Vicky Bihud, Nor Hadiani Ismail, Farida Zuraina Mohd Yusof

DOI: 10.7324/JAPS.2021.110410Pages: 076-087

Graphical Abstract

Synthesis, cytotoxicity, and promising anticancer potential of novel β-amino- and β-iminophosphonates

Vanya Koleva, Irina Yotova, Asya Dragoeva, Dobromir Enchev

DOI: 10.7324/JAPS.2021.110708Pages: 080-088

Graphical Abstract

A new curcumin analog, CCA-1.1, induces cell death and cell cycle arrest in WiDr colon cancer cells via ROS generation

Febri Wulandari, Muthi Ikawati, Mitsunori Kirihata, Jun-Ya Kato, Edy Meiyanto

DOI: 10.7324/JAPS.2021.1101014Pages: 099-105

Graphical Abstract

Mitochondrial pathway mediated apoptosis and cell cycle arrest triggered by cobalt(III) complex in Dalton’s lymphoma cells

Praveen Kumar Verma, Mannu Kumar Gond, Manoj Kumar Bharty, Arbind Acharya

DOI: 10.7324/JAPS.2021.1101002Pages: 007-015

Graphical Abstract

Evaluation of the cytotoxic activity of Tamarix articulata and its anticancer potential in prostate cancer cells

Abdullah M. Alnuqaydan, Abdulmajeed G. Almutary, Ohoud Y. Alshehri, Hanan Ali Henidi, Abdullah M. Alajlan, Abdullah Al Tamim, Abdullah Alowaifeer, Mohd Younis Rather, Bilal Rah

DOI: 10.7324/JAPS.2021.120209Pages: 089-108

Graphical Abstract

Quillaja saponaria bark saponin attenuates methotrexate induced hepatic oxidative stress, inflammation and associated liver injury in rats

Mustafa Ahmed Abdel-Reheim, Ahmed Amine Ashour, Mohamed Abdelrazik Khattab, Ahmed Gaafar A. Gaafar

DOI: 10.7324/JAPS.2022.120510Pages: 129-141

Graphical Abstract

Proapoptotic activity of essential oils from Syzygium aromaticum, Melaleuca cajuputi, and Cymbopogon nardus on HeLa human cervical cancer cells

Happy Kurnia Permatasari, Anita Dominique Subali, Muhammad Yusuf, Holipah Holipah

DOI: 10.7324/JAPS.2022.121209Pages: 084-094

Graphical Abstract

Combretum hypopilinum exhibited anti-inflammatory activity in LPS-stimulated RAW 264.7 murine macrophages through inhibition of inflammatory mediators and apoptosis

Kokou Idoh, Kossivi Dosseh, Mrinmoy Gautam, Tchazou Kpatcha, Natarajan Manikandan, Amegnona Agbonon, Muthiah Ramanathan, Messanvi Gbeassor

DOI: 10.7324/JAPS.2023.119177Pages: 193-198

Graphical Abstract

Comparative metabolite profiling of Eleutherine bulbosa ethanol and water extracts by UPLC-MS/MS and their cytotoxic effects on T47D cells

Roihatul Mutiah, Zawilatul Muzazanah, Rahmi Annisa, Ermin Rachmawati, Avin Ainur Fitrianingsih

DOI: 10.7324/JAPS.2024.176492Pages: 052-062

Graphical Abstract

Anti-proliferative activity and apoptotic induction of tannins extracted from Quercus infectoria on oral cancer KB cell lines

Fazil Ahmad, Krishna Mohan Surapaneni, Abeer Mohammed Al-Subaie, Balu Kamaraj

DOI: 10.7324/JAPS.2024.174009Pages: 184-199

Graphical Abstract

Africa leaf (Vernonia amygdalina Delille.) DCM extract synergistically supports growth suppression effect of doxorubicin on MCF7 and MCF7/HER2 with different effects on cell cycle progression and apoptosis evidence

Novia Permata Hapsari, Desty Restia Rahmawati, Nadzifa Nugraheni, Mila Hanifa, Denny Satria, Poppy Anjelisa Zaitun Hasibuan, Edy Meiyanto

DOI: 10.7324/JAPS.2024.180163Pages: 075-081

Graphical Abstract

The combination of fraction A3 of Cyrtostachys renda Blume with doxorubicin improved cytotoxicity against T47D cell line through cell cycle arrest and apoptotic induction

Syamsurizal Syamsurizal, Diah Tri Utami

DOI: 10.7324/JAPS.2024.173607Pages: 270-278

Graphical Abstract

SNEDDS to improve the bioactivities of Pandanus tectorius leaves: Optimization, antioxidant, and anticancer activities via apoptosis induction in human cervical cancer cell line

Alifa Husnun Kholieqoh, Murni Nur Islamiah Kassim, Tengku Sifzizul Tengku Muhammad, Khairul Anam, Yeong Yik Sung, Hermansyah Amir, Husna Nugraha Praja, Yosie Andriani

DOI: 10.7324/JAPS.2024.168694Pages: 175-189

Graphical Abstract

Sorafenib combination with imatinib enhances apoptotic and cell cycle arrest effects with no effect on viability and BCR-ABL expression of K-562 cells

Belal A. Al-Husein, Ahmad Al-Azayzih, Fatema S. Redha

DOI: 10.7324/JAPS.2024.161424Pages: 190-195

Graphical Abstract

Diterpene alcohol fraction of Cyperus rotundus Linn essential oil regulates Bcl-2 and Bax expression inducing apoptosis on HeLa in vitro and in silico

Susianti Susianti, Yanwirasti Yanwirasti, Eryati Darwin, Jamsari Jamsari, Arif Setiawansyah

DOI: 10.7324/JAPS.2024.188231Pages: 071-081

Graphical Abstract