Research Article | Volume: 3, Issue: 4, April, 2013

Synthesis, characterization and biological evaluations of some 5-(substituted amino alkyl)-2-{(1, 3- benzothiazole-2-yl)}-thiazolidine-4 one Mannich bases as potent antibacterial agents

Munendra Mohan Varshney Asif Husain Versha Percha Neeraj Fuloria   

Open Access   

Published:  Apr 27, 2013

DOI: 10.7324/JAPS.2013.3424
Abstract

Novel Mannich bases of 5-(substituted amino alkyl)-2-{(1, 3 benzothiazole-2-yl)}-thiazolidine-4 one, are synthesized by amination at 5th position of thiazolidine ring of 2-{(1, 3 benzothiazole-2-yl)}-thiazolidine-4 one using formaldehyde and various secondary amines. The synthesized compounds have been characterized by physico-chemical and spectral analysis and screened for their in- vitro antibacterial activity against various strains of bacteria.


Keyword:     Thiazolidinone Benzothiazole Antibacterial Mannic


Citation:

Asif Husain, Munendra Mohan Varshney, Versha Percha, Neeraj Fuloria., Synthesis, characterization and biological evaluations of some 5-(substituted amino alkyl)-2-{(1, 3- benzothiazole-2-yl)}- thiazolidine-4 one Mannich bases as potent antibacterial agents. J App Pharm Sci, 2013; 3 (04): 135-138.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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