Research Article | Volume : 1 Issue : 4, June 2011

Synthesis and Antimicrobial studies of novel Benzimidazole derivatives

Parmender Singh RatheeRitu Dhankar Sunny BhardwajMonika Gupta Rakesh Kumar   

Open Access   


Two series of novel benzimidazole derivatives were synthesized. The first one comprise of 2-methyl, the second one comprise of 2-phenyl substitution on benzimidazole moiety. Seven novel benzimidazole derivatives were synthesized successfully in appreciable yields and characterized physicochemically. The structures of all the synthesized derivatives were confirmed by IR and 1HNMR. Furthermore, the synthesized compounds were screened for antimicrobial activity (antibacterial activity and antifungal activity) by tube dilution method. Some of the synthesized compounds showed appreciable antifungal activity.

Keyword:     Substituted benzimidazoles antimicrobial activity antifungal activity antibacterial activity

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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