Research Article | Volume: 2 Issue: 9, September, 2012
Open Access DOI: 10.7324/JAPS.2012.2921
Scientific evaluated that, anti-inflammatory and analgesic activity of ethanol with water in the ratio of 3:1 extracts were obtained from different parts viz., leaves, seeds and latex of Excoecaria agallocha. The latex was sequentially soxhlated with petroleum ether and methanol dried latex in anti-inflammatory processes and analgesic activity in two concentrations (250 mg/kg and 500 mg/kg). Preliminary phytochemical analysis showed that, presence of alkaloids, flavanoids, saponins were found maximum in the seed extract. Acute inflammatory studies showed that, latex, leaves and seed extracts of both concentration of chosen plant produced significant inhibition of carrageenin induced rat paw edema at 3rd hour (p<0.005) as compared to the control causing 63.15%, 62.15% and 69.69% respectively. In addition that, the seed extract at the concentration of 500 mg/kg showed maximum inhibition at 57.03% as compared to control in cotton pellet induced granuloma test. The analgesic activity of seed extract at the dose of 500 mg/kg. caused significant inhibitions in the acetic acid induced writhing. Moreover, the tail immersion model, seed extract at the concentration of 500 mg/kg. possess an maximum activity (80.29%) as compared to control.
M. Babuselvam, S. Ravikumar, K.A Mohamed Farook, S. Abideen, M. Peer Mohamed and M. Uthiraselvam. Evaluation of antiinflammatory and analgesic effects on the extracts of different parts of Excoecaria agallocha L. J App Pharm Sci. 2012; 2(9): 108-112.
Year
Month
Anti-inflammatory and antidiabetic activity of ethanolic extracts of Sterculia villosa barks on Albino Wistar rats
Anti-inflammatory activity of fractionated extracts of Salvia officinalis
Valeria Dal Pra, Lais B. Bisol, Suelen Detoni, Marjorie Denti, Jaine Grando, Camila Pollo, Tiago R. Pasquali, Arno Ernesto Hoffmann, Marcio A. Mazutti, Sandra M. D. MacedoThe Analgesic Effect of a Curcumin Analogue 1,5-bis(4’-hydroxy-3’-methoxyphenyl)-1,4-pentadien-3-on (Gamavuton-0) in acute and persistent pain
Milky Mangrove Excoecaria agallocha L. Plant as a source for potential mosquito larvicides
Anti-inflammatory and antinociceptive activity of pods of Caesalpinia pulcherrima
Manoj Kumbhare, Thangavel SivakumarElucidation of Analgesic and Antipyretic activities of Ficus bengalensis linn. Leaves in rats
Sachdev Yadav, Mayank Kulshreshtha, Mradul Goswami, Chandana V. Rao, Veena Sharma