Open Access DOI: 10.7324/JAPS.2012.2544
Four sensitive and precise spectrophotometric methods were developed and validated for the simultaneous determination of pioglitazone hydrochloride (PGZ) and glimepiride (GLM) in their pharmaceutical formulations. Among the methods adopted were direct absorbance, firstderivative (1D), second-derivative (2D) and first-derivative of ratio spectra (1DD). The selectivity of the proposed methods was checked using laboratory prepared mixtures. The proposed methods were successfully applied to the analysis of GLM and PGZ in their mixture and in pharmaceutical dosage forms without interference from other additives.
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Derivative Spectrophotometric Methods for the Determination of Zolpidem Tartrate in Tablets
Analytical method development and validation for the simultaneous estimation of pioglitazone and glimepiride in tablet dosage form by multiwavelength spectroscopy
Indrajeet Singhvi, Khushboo Mehta, Nidhi KapadiyaBiochemical Effects of Some Peroxisome Proliferator Activated Receptor Ligands in Hyperhomocysteinemic-rats