Research Article | Volume : 2 Issue : 5, May 2012

Evaluation of the Antioxidant and Anti-Cholineesterase activities of the Stem, Barks and Leaves of the Plant Vernonia Cinerea (Family: Asteraceae)

Md. Ahsanul Haque,  Chowdhury Sayef Abdullah,  Md Musfizur Hassan,  Most. Nazma Parvin,  Md. Bodruddoza Rafique,  A.G.M. Mostofa   
Md. Ahsanul Haque1, Chowdhury Sayef Abdullah1, Md Musfizur Hassan2, Most. Nazma Parvin1, Md. Bodruddoza Rafique1, A.G.M. Mostofa1

1Department of Clinical Pharmacy & Pharmacology, University of Dhaka, Bangladesh.

2Department of Pharmacy, Jahangirnogor University, Bangladesh.

Open Access    DOI: 10.7324/JAPS.2012.2543

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Abstract

The aim of this study was to evaluate the anti-oxidant and anti-choline esterase activity of the stem, barks and leaves of the plant V. cinerea. The stems, barks and the leaves of the plant V.Cineria was sun dried and extracted using methanol. The anti-oxidant activity of the crude methanolic extract was measured by the DPPH free radical scavenging activity. The crude methanolic extract showed significant anti-oxidant activity by the DPPH free radical scavenging method. Evaluation of ChEs enzyme activity of the crude methanolic extract was done by Ellman method. The methanolic extract of V. cinerea leaves exerted significant AChE and BChE inhibitory effects.


Keyword:     Vernonia cinerea anti-oxidant DPPH Kanamycin acetylcholinesterase (AChE) butyryl-cholinesterase (BChE).

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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