Antioxidants are frequently used in several dietary supplements and have been probed for their significant role in the prevention of diseases like cancer or coronary heart disease. Acetyl salicylic acid has grabbed substantial attention due to their ability in impeding oxidative stress. In the present study, nine new salicylic acid derivatives: 5-(2-hydroxyphenyl-5-substituted)-1,3,4-oxadiazole-2(3H)-thiones, N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxy-5-substituted benzamides, 2-hydroxy-5-substituted-N'-[1-(2-oxo-2substituted-chromen-3-yl)ethylidene] benzohydrazides and Hg (II) complex of N'-[(1Z)-1-(6-bromo-2-oxo-2H-chromen-3-yl) ethylidene]-2-hydroxybenzohydrazide have been synthesized and characterized in the light of advanced spectral techniques. The antioxidant properties of these compounds were investigated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) spectrometric assay and compared with the results of cyclic voltammetry studies. The redox properties shown by the active molecule using cyclic voltammetry correlated well with the biochemical study.
Poojari J, Sunil D, Kamath PR, Kulal A, Puttanna KD. Antioxidant Properties and Electrochemical Behavior of some Acetyl Salicylic Acid Derivatives. J App Pharm Sci, 2016; 6 (11): 165-171.
Year
Month
Anti-Inflammatory Activities of Methanol Leaf Extract of Bridelia micrantha (Hochst) Baill. (Euphorbiaceae) in Wistar Rats
Evaluation of phytoconstituents, nephro-protective and antioxidant activities of Clitoria ternatea
K.Sarumathy, M.S.Dhana Rajan, T.Vijay, J.JayakanthiAntibacterial, antioxidant, and anticancer activities of Penicillium citrinum Thom. endophytic in Jatropha heynei
Gowdru Basanna Ashoka, Manchanahally Byrappa Shivanna