Research Article | Volume: 5, Issue: 10, October, 2015

Antibacterial and antioxidant activities of methanolic leaf extract of Maerua crassifolia

Kingsley Chimsorom Ckilaka Godwin Christian Akuodor Joseph Linus Akpan Emeka Daniel Ogiji Chukwuemeka Okorie Eze Basil Chukwuma Ezeokpo   

Open Access   

Published:  Oct 28, 2015

DOI: 10.7324/JAPS.2015.501025

The objective of this study was to investigate the antibacterial and antioxidant activities of the methanol leaf extract of Maerua crassifolia, an important medicinal plant used in Nigeria. The antibacterial properties of the methanol extract were studied against clinically important bacteria viz; Staphylococcus aureus, Shigella spp., Salmonella typhi, Bacillus subtilis and Escherichia coli by disc diffusion method. The free radical scavenging potential of the extract was assessed by measuring its capability for scavenging 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical. The methanol leaf extract of Maerua crassifolia at the concentration of 12.5-150 µg/ml, showed significant activity against all the tested organisms. The observed antioxidant activity of the leaf extract suggests that the extract is a potential source of natural antioxidant and could be useful in the treatment of diseases.

Keyword:     Maerua crassifolia leaf extract methanol antibacterial agent DPPH antioxidant.


Chilaka KC, Akuodor GC, Akpan JL, Ogiji ED, Eze CO, Ezeokpo BC. Antibacterial and antioxidant activities of methanolic leaf extract of Maerua crassifolia. J App Pharm Sci, 2015; 5 (10): 147- 150.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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