Short Communication | Volume: 5, Issue: 10, October, 2015

Antimicrobial alkaloids from the leaves of Pandanus amaryllifolius

Hanna Mae C. Laluces Atsushi Nakayama Maribel G. Nonato Thomas Edison dela Cruz Mario A. Tan   

Open Access   

Published:  Oct 28, 2015

DOI: 10.7324/JAPS.2015.501026

Chemical investigation on the crude base of the Pandanus amaryllifolius leaves led to the isolation and identification of pandamarilactone-1 (1), pandamarilactone-32 (2), pandamarilactonine-A (3), and pandamarilactonine-B (4). Their structures were elucidated based on 1H and 13C NMR and in comparison with the literature data. Compound 3 was found to be the most active among the four isolates with an MIC of 15.6 µg/mL and MBC of 31.25 µg/mL against Pseudomonas aeruginosa. This is the first report on the antimicrobial activity of the isolated alkaloids from the genus Pandanus.

Keyword:     Pandanus Pandamarilactonine Pandamarilactone Pandanus amaryllifolius MIC MBC.


Hannah Mae Laluces, Atsushi Nakayama, Maribel Nonato, Thomas Edison dela Cruz, Mario Almoite Tan. Antimicrobial alkaloids from the leaves of Pandanus amaryllifolius. J App Pharm Sci, 2015; 5 (10): 151-153.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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