Research Article | Volume : 2 Issue : 3, March 2012

Synthesis and antimicrobial study of N-[4-(2-piperidine-1-yl-ethoxy) phenyl] acetamide analogues

H. P. Jayadevappa,  G. Nagendrappa,  S. Umesha,  S. Chandrashekar   
H. P. Jayadevappa1, G. Nagendrappa1, S. Umesha2, S. Chandrashekar2

1Department of Studies in Chemistry, Manasagangotri, Mysore 570 006, Karnataka, India.

2Department of Studies Applied Botany and Biotechnology2, Manasagangotri, Mysore 570 006, Karnataka, India.

Open Access    DOI: 10.7324/JAPS.2012.2331

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Abstract

In the present study, a novel series of N-[4-(2-piperidine-1-yl-ethoxy) phenyl]-acetamides were synthesized from 4-aminophenol and characterised by IR, 1H-NMR, Mass spectral studies and elemental analysis. The antimicrobial potency of compounds is tested against variety of fungal and bacterial strains by disc agar diffusion technique. in comparison to to fluconazole and chloramphenicol respectively. Some of the synthesized compounds exhibit the potency comparable to that of standard drugs.


Keyword:     N-[4-(2-piperidine-1-yl-ethoxy)phenyl]-acetamide Sy

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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