Research Article | Volume: 2 Issue: 7, July 2012

Antioxidant response of Camellia sinensis and Rosmarinus officinalis aqueous extracts toward H2O2 stressed mice

Lahlou Fatima Azzahra Hmimid Fouzia Loutfi Mohammed Bourhim Noureddine   

Open Access    DOI: 10.7324/JAPS.2012.2708

Abstract

Oxidative stress takes place when the balance between the antioxidant defenses and the generation of reactive oxygen species (ROS) is tipped in favor of the latter. Thus, hydrogen peroxide (H2O2) is directly involved in the production of ROS due to his high redox level. However aqueous extracts of green tea and rosemary have been investigated to be evaluated for their antioxidant properties. And the metabolic enzymes and antioxidant defense biomarkers were assessed. The results obtained revealed that in green tea and rosemary extracts groups, superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) activities in liver decreased significantly compared to groups treated with H2O2, as well as malondialdehyde in groups treated with both extracts. This study showed that green tea and rosemary extracts has an excellent antioxidant activities which is confirmed by determining the a,a-diphenyl-b-pricrylhydrazyl(DPPH) radical scavenging activities.


Keyword:     Oxidative stresshydrogen peroxideantioxidantgreen tearosemary.


Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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