Review Article | Volume : 2 Issue : 6, June 2012

Coumarin: Chemical and Pharmacological Profile

P. K. Jain Himanshu Joshi   

Open Access    DOI: 10.7324/JAPS.2012.2643

Abstract

Coumarins are classified as a member of the benzopyrone family. all of which consist of a benzene ring joined to a pyrone ring. The benzopyrones can be subdivided into the benzo-alfa-pyrones to which the coumarins belong and the benzo-gama-pyrones, of which the flavonoids are principal members. Umbelliferone, esculetin and scopoletin are the most widespread coumarins in nature. During the synthesis of these compounds ortho-hydroxylation should respectively take place on p-coumaric, caffeic and ferulic acid. The coumarins are of great interest due to their pharmacological properties. In particular, their physiological, bacteriostatic and anti-tumor activity makes these compounds attractive backbone derivatisation and screening as novel therapeutic agents.


Keyword:     Coumarin benzopyrone flavonoids anti-tumor activity bacteriostatic


Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text

Reference

Article Metrics
518 Views 319 Downloads 837 Total

Year

Month

Related Search

By author names