Review Article | Volume : 2 Issue : 5, May 2012

Nanocarrier-Based Drugs: The Future Promise for Treatment of Breast Cancer

Yieldez Bassiouni Laila Faddah   

Open Access    DOI: 10.7324/JAPS.2012.2530

Abstract

Breast cancer is by far the commonest cancer in women; more than 1 million women world wide are diagnosed with breast cancer every year. Treatment options of breast cancer are surgery, radiation and chemotherapy. Although there have been significant advances in breast cancer treatment over the past several decades, current therapeutic approaches are limited by non-specific systemic distribution, inadequate drug concentrations reaching the tumor and multidrug resistance.The application of nanotechnology to medicine helps to overcome limitations relating to chemotherapy. Nanoparticles with enhanced surface properties are able to diffuse with greater ease inside the tumor cells delivering a high amount of drug selectively to tumor cells with significant reduced toxicity.In the near future, the use of nanotechnology could revolutionize the entire of breast cancer treatment. The present review examined some of the approved nanocarrier-based drugs for treatment of breast cancer. Also, other drugs under development or in preclinical trials to be used in the near future will be discussed.


Keyword:     Breast cancer anticancer drugs nanotechnology nanoparticles gene therapy.


Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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