Research Article | Volume : 1 Issue : 10, December 2011

Synthesis and antimicrobial studies of substituted 2-phenylbenzimidazole derivatives

Parmender Singh Rathee Ritu Dhankar Sunny Bhardwaj Monika Gupta Rakesh Kumar   

Open Access   


The substituted 2-phenylbenzimidazole derivatives were synthesized by introducing different substituents at different positions. Six novel benzimidazole derivatives were synthesized successfully in appreciable yields and characterized physicochemically. The structures of all the synthesized derivatives were confirmed by IR and 1HNMR. Furthermore, the synthesized compounds were screened for antimicrobial activity (antibacterial activity and antifungal activity) by tube dilution method. Some of the synthesized compounds showed appreciable antifungal activity.

Keyword:     Benzimidazole antimicrobial activity antifungal activity antibacterial activity

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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