Case Report | Volume: 6, Issue: 12, December, 2016

Cefoperazone: A Rare Cause of Thrombocytopenia

A. Avinash Sushil Kiran Kunder Bharti Chogtu Magazine K. L. Bairy Shalini Adiga   

Open Access   

Published:  Dec 28, 2016

DOI: 10.7324/JAPS.2016.601227

Beta lactam antibiotics are one of the most commonly prescribed antibiotic drug classes in medical practice. Cephalosporins differ from other beta lactam antibiotics in both their structure and spectrum of action. Beta lactam antibiotics, in general, may cause platelet deficiency owing to their interference with normal platelet function. Cefoperazone, belonging to the group of 3rd generation cephalosporins, has been reported to cause hypoprothrombinemia and hence, bleeding manifestations. However, it is not known to alter platelet function and count at the routinely used therapeutic doses. This case report highlights a rare case of cefoperazone-induced thrombocytopenia.

Keyword:     Platelet Beta-LactamCephalosporins Antibiotic BleedingHypoprothrombinemia.


Avinash A, Kunder SK, Magazine BC, Bairy KL, Adiga S, Patil N. Cefoperazone: A Rare Cause of Thrombocytopenia. J App Pharm Sci, 2016; 6 (12): 190-191.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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