Research Article | Volume: 5, Issue: 12, December, 2015

GC-MS characterization of n-hexane soluble compounds of Cyperus rotundus L. rhizomes

Hema Nidugala Ramakrishna Avadhani Ashwini Prabhu Ravishankar Basavaiah K N Sunil Kumar   

Open Access   

Published:  Dec 27, 2015

DOI: 10.7324/JAPS.2015.501216
Abstract

Cyperus rotundus L., popularly known as nutgrass or nagarmotha, is commonly used in the traditional medicine for inflammatory disorders. In the present study, n-hexane extract from rhizomes of C. rotundus (HCR) was analyzed for its constituents using GC-MS technique. The rhizomes were collected, washed, shade dried and powdered. N-hexane extract was prepared by cold percolation method and preliminary phytochemical screening was carried out. It was subjected to Gas Chromatography coupled with Mass Spectroscopy (GC-MS) for the identification of components thereon. Preliminary phytochemical screening of HCR revealed the presence of phenolics, sterols and terpenoids. GC-MS data indicates the presence of twenty seven low polar components in HCR. The major identified molecules include hentriacontane (7.15%), triacontane (6.12%), nonacosane (5%), octacosane (4.38%), octadecane (2.35%), hexadecane (2.32%), eicosane (1.56%), pentatriacontane (1.43%), 9-di-tert-butyl-1-oxaspiro(4,5)deca-6,9-diene-2,8-dione (1.37%), Heneicosane, 3-methyl- (1.27%), α-cyperone (1.25%), heptadecane (1.15%) and gamma-Sitosterol (1%). As some of these constituents are known to possess anticancer activity, HCR could be used as an active therapeutic ingredient.


Keyword:     Cyperus rotundus GC-MS analysis phytoconstituents volatile constituents anticancer.


Citation:

Nidugala H, Avadhani R, Prabhu A, Basavaiah R, Sunil Kumar KN. GC-MS characterization of n-hexane soluble compounds of Cyperus rotundus L. rhizomes. J App Pharm Sci, 2015; 5 (12): 096-100.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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