Research Article | Volume: 5, Issue: 12, December, 2015

In vitro Cytotoxicity and Glucose Uptake Activity of Fruits of Terminalia bellirica in Vero, L-6 and 3T3 cell lines

Mary Shoba Das Gayathri Devi   

Open Access   

Published:  Dec 27, 2015

DOI: 10.7324/JAPS.2015.501215
Abstract

Terminalia bellirica is a native plant of India belonging to the family Combrataceae. The aim of the present study is to evaluate the cytotoxicity and glucose uptake activity of ethanolic extract of fruits of Terminalia bellirica using Vero, L-6 and 3T3 cell lines. The results showed that the extracts did not confer any cytotoxicity and the ethanolic extract showed better glucose uptake potential. The results were compared with insulin and metformin, which were used as the standard antidiabetic drugs. Insulin (1IU/ml) and metformin (100 µg/ml) enhance the glucose uptake over control.


Keyword:     Cytotoxicity glucose uptake insulin metformin.


Citation:

Das MS, Devi G. In vitro Cytotoxicity and Glucose Uptake Activity of Fruits Terminalia bellirica in Vero, L-6 and 3T3 cell lines. J App Pharm Sci, 2015; 5 (12): 092-095.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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