Research Article | Volume: 5, Issue: 9, September, 2015

Analgesic and antihyperglycemic activity evaluation of Bambusa vulgaris aerial parts

A. K. M. Mahmudul Haque Anuj Kumer Das Shamrat Shafiul Bashar Rahat Al-Mahamud Mohammed Rahmatullah   

Open Access   

Published:  Sep 27, 2015

DOI: 10.7324/JAPS.2015.50924
Abstract

Bambusa vulgaris, also known as ‘Ora Bansh’ in Bangladesh is grown throughout the country for housing and scaffolding purposes. As part of our analgesic and antihyperglycemic plants of Bangladesh screening program, it was of interest to evaluate the analgesic and antihyperglycemic potential of aerial parts of the plant. Methanolic extract of aerial parts (MEBV) at doses of 50, 100, 200 and 400 mg per kg significantly reduced the number of writhings in acetic acid-induced pain model Swiss albino mice by 25.9, 29.6, 37.0, and 44.4%, respectively compared to reductions of 40.7 and 51.9%, respectively, obtained with 200 and 400 mg per kg of a standard analgesic drug, aspirin. MEBV, at doses of 100, 200 and 400 mg per kg also significantly lowered blood glucose levels in mice, respectively, by 32.8, 45.8, and 55.3% compared to control mice. A standard antihyperglycemic drug, glibenclamide, when administered at a dose of 10 mg per kg lowered blood glucose level by 50.8%. Taken together, the results indicate that the aerial parts of the plant possess considerable analgesic and antihyperglycemic potential, which can possibly be attributed to the presence of alkaloids and saponins in the extract.


Keyword:     Analgesic Bambusa vulgaris antihyperglycemic Poaceae.


Citation:

University of Development Alternative, Dhaka, Bangladesh., Analgesic and antihyperglycemic activity evaluation of Bambusa vulgaris aerial parts. J App Pharm Sci, 2015; 5 (09): 127-130.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text

Reference

Article Metrics
402 Views 49 Downloads 451 Total

Year

Month

Related Search

By author names