Research Article | Volume: 5, Issue: 1, January, 2015

Antinociceptive, anti-gastric ulcerogenic and anti-inflammatory activities of standardized egyptian pomegranate peel extract

Rola Milad Labib Sherweit Hamed El-Ahmady   

Open Access   

Published:  Jan 30, 2015

DOI: 10.7324/JAPS.2015.50109

The utilization of the peels of the widely popular pomegranate fruit is the subject of this study. This bio waste product, which has been under study for some time as a source of potential bioactive constituents is investigated for its biological activity. A method for the extract standardization was developed using HPLC and ellagic acid as a reference standard. Results revealed that the pomegranate methanolic extract exhibited potent analgesic and anti-inflammatory activity comparable to indomethacin, used as a reference, and furthermore, caused no gastric ulcer formation.

Keyword:     Punica husk ellagic acid HPLC antinociceptive anti-gastric ulcerogenic anti-inflammatory.


Rola Milad Labib, Sherweit Hamed El-Ahmady. Antinociceptive, Anti-gastric ulcerogenic and Anti-inflammatory Activities of Standardized Egyptian Pomegranate Peel Extract. J App Pharm Sci, 2015; 5 (01): 048-051.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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