Research Article | Volume: 3, Issue: 12, December, 2013

GC-MS analysis and antifungal activity from galls of Guiera senegalensis J.F Gmel (Combretaceae)

Pierre AED Sombié,  Kiessoum Konate,  Estelle Youl,  Ahmed Y Coulibaly,  Martin Kiendrébéogo,  Muhammad I Choudhary,  O G Nacoulma   
Pierre AED Sombié1, Kiessoum Konate1, Estelle Youl2, Ahmed Y Coulibaly1, Martin Kiendrébéogo1, Muhammad I Choudhary3, O G Nacoulma1

1Laboratory of Biochemistry and Chemistry Applied (LABIOCA), University of Ouagadougou, Burkina Faso.

2Laboratory of Pharmacology and Toxicology, University of Ouagadougou, Burkina Faso.

3International Center of Chemistry and Biological Sciences (ICCBS), University of Karachi, Pakistan.

Open Access   

Published:  Dec 30, 2013

DOI: 10.7324/JAPS.2013.31202
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Abstract

Guiera senegalensis is a well known medicinal plant which is used as a drug in Burkina Faso. The aim of this study was to investigate the chemical composition and antifungal activity from galls of Guiera senegalensis against different kinds of fungi in vitro. The chemical composition of the Guiera senegalensis volatile compounds obtained from the galls was analysed using gas chromatograph (GC)-flame ionization detectors (FID) and GC-MS. Thirteen (13) components were identified for hexane-acetone (50:50) column fraction of hydroacetone extract and twenty one (21) compounds for hexane-acetone (50:50) column fraction of aqueous decoction extract. This composition differed according to the kind of extract. The ethyl acetate fraction extract from hydroacetone extract (EAF/HAE) exhibited the highest of flavonol content (0.56 ± 0.01 mg QE/100 mg of fraction). The G. senegalensis exhibited an interesting antifungal activity against all strains tested.


Keyword:     Galls Guiera senegalensis Volatile compounds Flavonols content Antifungal activity.

Citation:

Pierre AED Sombié, Kiessoum Konate, Estelle Youl, Ahmed Y Coulibaly, Martin Kiendrébéogo, Muhammad I Choudhary, O G Nacoulma. GC-MS analysis and antifungal activity from galls of Guiera senegalensis J.F Gmel (Combretaceae). J App Pharm Sci, 2013; 3 (12): 006-012.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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