Published:  Jul 30, 2013DOI: 10.7324/JAPS.2013.3725
A series of 5-benzylidene-3-α-carboxy ethylrhodanine derivatives (3a-m) were synthesized using 3-α-carboxy ethylrhodanine with various substituted aromatic aldehydes in anhydrous sodium acetate in glacial acetic acid by the knoevenagal condensation under microwave irradiation. The compounds synthesized within short time 10-15 min and in good yields. All the compounds characterized by IR, UV, 1H & 13C-NMR and MS spectral data and studied in vitro antibacterial activity.
Kaveri Sundaram and Subban Ravi., Microwave assisted synthesis of 3-α-carboxy ethylrhodanine derivatives and their in vitro antibacterial activity. J App Pharm Sci, 2013; 3 (07): 133-135.
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