Research Article | Volume: 3, Issue: 7, July, 2013

Microwave assisted synthesis of 3-α-carboxy ethylrhodanine derivatives and their in vitro antibacterial activity

Kaveri Sundaram and Subban Ravi   

Open Access   

Published:  Jul 30, 2013

DOI: 10.7324/JAPS.2013.3725
Abstract

A series of 5-benzylidene-3-α-carboxy ethylrhodanine derivatives (3a-m) were synthesized using 3-α-carboxy ethylrhodanine with various substituted aromatic aldehydes in anhydrous sodium acetate in glacial acetic acid by the knoevenagal condensation under microwave irradiation. The compounds synthesized within short time 10-15 min and in good yields. All the compounds characterized by IR, UV, 1H & 13C-NMR and MS spectral data and studied in vitro antibacterial activity.


Keyword:     3-α-carboxy ethylrhodanine antibacterial activity microwave irradiation.


Citation:

Kaveri Sundaram and Subban Ravi., Microwave assisted synthesis of 3-α-carboxy ethylrhodanine derivatives and their in vitro antibacterial activity. J App Pharm Sci, 2013; 3 (07): 133-135.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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