Research Article | Volume: 3, Issue: 3, March, 2013

Radical scavenging and In-Vitro Hemolytic Activity of Aqueous Extracts of Selected Acacia Species

Sulaiman C.T. and Gopalakrishnan V.K.   

Open Access   

Published:  Mar 28, 2013

DOI: 10.7324/JAPS.2013.30321
Abstract

The aqueous extracts of three Acacia species were screened for their free radical scavenging and in vitro hemolytic activity. The total phenolic content was also determined in all the three species. The total phenolics were estimated spectrophotometrically based on the reduction of phosphomolybdate ion of Folin-Ciocalteu reagent and was expressed as milligram equivalent of Gallic acid. The radical scavenging activity was evaluated by DPPH assay. Acacia nilotica showed maximum radical scavenging activity with EC50 12.5. Hemolytic activity of the aqueous extracts was screened against normal human erythrocytes. Aqueous extract of A. lucophloea possessed minimum hemolytic activity where as A.nilotica showed highest hemolytic activity.


Keyword:     Acacia Phenolics DPPH Hemolytic activity.


Citation:

Sulaiman C T and Gopalakrishnan V K., Radical scavenging and In-Vitro Hemolytic Activity of Aqueous Extracts of Selected Acacia Species. J App Pharm Sci. 2013; 3 (03): 109-111.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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