Research Article | Volume: 3, Issue: 2, February, 2013

Evaluation of the Antioxidant and Hepatoprotective Activity of Cryptolepis Buchanani

K. Padmalochana ,  M.S. Dhana Rajan,  R.Lalitha,  H.Sivasankari   
K. Padmalochana1 & 2, M.S. Dhana Rajan3, R.Lalitha4, H.Sivasankari5

1Research and development centre, Bharathiar University, Coimbatore.

2P.G Dept. of Biochemistry, Sri Akilandeswari Women's College, Wandiwash, Tamil Nadu, India.

3Dept of Biochemistry Jaya college of Arts & Science,Tiruninravur, Chennai , India.

4PG & Research Dept of Microbiology, Kamban College of Arts and Science for women, Tiruvannamalai, Tamilnadu, India.

5PG Department of biotechnology, Arunai Engineering college, Anna Bioresearch foundation, Tiruvannamalai, Tamilnadu, India.

Open Access   

Published:  Feb 27, 2013

DOI: 10.7324/JAPS.2013.30217
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Abstract

Cryptolepis buchanani (Berberidaceae) is a climbing tree, leaves is widely used in folk medicine in Southeast Asia. The alcoholic extract of stem of this plant is commonly used for the treatment of inflammatory conditions such as arthritis, and muscle and joint pain. The development of hepatotoxicity induced by acetaminophen is promoted by oxidative stress. The aim of the present study was to investigate the hepatoprotective effect and antioxidant activities of the ethanolic extract of Cryptolepis buchanani on acetaminophen induced hepatotoxicity in rats. We observed that the ethanolic extract of cryptolepis buchanani conferred hepatoprotectivity. Biochemical observations confirmed the beneficial roles of Cryptolepis buchanani and silymarin against acetaminophen induced liver injury in rats.


Keyword:     Hepatoprotective Cryptolepis buchanani<

Citation:

K. Padmalochana, M.S. Dhana Rajan, R. Lalitha, H.Sivasankari., Evaluation of the Antioxidant and Hepatoprotective activity of Cryptolepis Buchanani. J App Pharm Sci. 2013; 3 (02): 099-104.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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