Published:  Feb 27, 2013DOI: 10.7324/JAPS.2013.30216
Paediatric antibiotic prescription is a major concern in terms of public health, since infections are the most frequent cause of childhood disease. The aim of this a hospital-based cross sectional study was to assess the pattern of antibiotic use in the Paediatric ward of Hawassa University referral hospital, southern-Ethiopia. Data was entered into a computer and statistical analysis was done using SPSS for windows version16. From the result of the study, the frequency and percentage of antibiotic prescriptions identified was 1381 (74.7%); (Wald test, p < 0.01), and the frequency and percentage of Injectable prescription was 1729 (93.6%); (Wald test, p < 0.01). The mean number of drugs prescribed per-prescription was 1.58±0.743. The mean of antibiotics prescriptions in preschool children was relatively higher (1.26; 95% C.I b/n 1.03-1.29) compared to other pediatric age groups. The use of antibiotic by pediatric age category was found to be significant (Pearson Chi-Square P= 0.037). Very strong positive correlation of antibiotic use was observed with generics prescriptions and injection prescriptions (0.740 and 0.731 with p-value < 0.01) respectively. The potential Drug-Drug Interactions (DDIs) identified in the study area was 66% (Fisher's Exact Test, P< 0.01). The availability of a set of key antimicrobial drugs in the hospital stores on the day of the study was 90.1%. The most frequently prescribed single antibiotic was penicillin G crystalline 146 (28.4%), While the most commonly prescribed multiple antibiotic prescriptions was ‘Ampicillin inj plus Gentamicin inj’ 113 (27%) followed by ‘Chloramphenicol inj plus Cloxacillin inj’ 60 (14.4%). From the result we can conclude that, there was a significant oral and injectable antibiotic utilization in the study area compared to similar studies conducted in other part of the world.
Minyahil A. Woldu, Sultan Suleman, Netsanet Workneh and Haftay Berhane., Retrospective Study of the Pattern of Antibiotic Use in Hawassa University Referral Hospital Pediatric Ward, Southern Ethiopia. J App Pharm Sci. 2013; 3 (02): 093-098.
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