Open Access DOI: 10.7324/JAPS.2012.21219
This study was designed to evaluate the hepatoprotective and antioxidant effect of ethanol extract of whole plant of Cynoglossum zeylanicum on CCl4 induced hepatotoxicity in rats. Activities of liver marker enzymes, SGOT, SGPT and ALP, total protein, albumin, globulin, total, conjugated and unconjugated bilirubins at an oral dose of ethanol extract of Cynoglossum zeylanicum (50, 100 and150mg/kg) showed a significant hepatoprotective effect. Regarding antioxidant activity, ethanol extract of Cynoglossum zeylanicum exhibited a significant effect showing increasing levels of SOD, CAT, GPx, GSH and GRD by reducing malondialdehyde (MDA) levels.
Anitha M., Daffodil E.D., Muthukumarasamy S., and Mohan V.R., Hepatoprotective and Antioxidant Activity of Ethanol Extract of Cynoglossum zeylanicum (Vahl ex Hornem) Thurnb ex Lehm In CCl4 -Treated Rats J App Pharm Sci. 2012; 2 (12): 099-103.
Year
Month
Hepatoprotective activity of Melia azedarach leaf extract against simvastatin induced Hepatotoxicity in rats
Evaluation of antioxidant, antibacterial, antifungal and cytotoxic effects of Clausena suffruticosa ethanolic root extract
Md. Atiar Rahman, Joti Sankhar Chakma, Saiful Islam, Nazim Uddin AhmedAntioxidant mediated defense role of Wedelia calendulacea herbal extract against CCl4 induced toxic hepatitis
S. Carmel Punitha, M.RajasekaranPattern of BAER abnormalities in neonatal hyperbilirubinemia
Cytotoxic effect and apoptotic activity of Parmentiera edulis DC. hexane extract on the breast cancer cell line MDA-MB-231