Research Article | Volume: 2 Issue: 12, December, 2012

Phytochemical Analysis and Cardiac Depressant Activity of Aqueous Methanolic Extract of Morus nigra L. Fruit

Muhammad Nasir Hayat Malik Alamgeer Ume Salma Abdul Qayyum and Sadia Samreen   

Open Access    DOI: 10.7324/JAPS.2012.21207

Abstract

The present study was conducted to investigate the effects of aqueous methanolic extract of Morus nigra L. fruiton frog's heart.Force of contraction and heart rate were measured by force displacement transducer attached to Power Lab data acquisition system. Lab chart Pro 5 software was used for the acquisition and analysis of data. The extract was also screened for various phytochemical constituents using standard methods. The results indicated that the extract produced a significant dose dependent decrease in heart rate without affecting the contractility of the heart. Phytochemical analysis also revealed that the extract contained flavonoids, cardiac glycosides,alkaloids, saponins and phenolic compounds.It is conceivable therefore; that the negative chronotropic effectsof aqueous methanolic extract of Morus nigra L. fruit may be attributed to the presence of certain pharmacologically active compounds.


Keyword:     Morus nigra L. Cardiovascular Phytochemical Frogs.


Citation:

Muhammad Nasir Hayat Malik, Alamgeer, Ume Salma, Abdul Qayyum, Sadia Samreen., Phytochemical Analysis and Cardiac Depressant Activity of Aqueous Methanolic Extract of Morus nigra L. Fruit. J App Pharm Sci. 2012; 2 (12): 039-041.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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