Research Article | Volume: 2 Issue: 9, September, 2012

Effect of Saccharum spontaneum Linn. on Lysosomal enzymes of Uro-lithiatic rats

M. Sathya and R. Kokilavani   

Open Access    DOI: 10.7324/JAPS.2012.2924

Abstract

The ethanolic root extract of Saccharum spontaneum of family Poaceae was used to treatthe urolithiasis induced by glycolic acid On this course, the extract also repairs the changesthat happened in the lysosomal enzymes like β-D-glucuronidase, xanthine oxidase in liver and kidney and n-acetyl -d-glucosaminidase in serum, liver, kidney and urine of the urolithiatic rats. The ethanolic root extract (200 and 300 / kg b.w.) elevated the levels of reduced β-D-glucuronidasein liver and n-acetyl -d-glucosaminidase in liver and kidney and reduced the level of xanthineoxidase in liver and kidney and n-acetyl -d-glucosaminidase in serum and urine significantly (p<0.05) when compared with the toxic groups. The results shown by the ethanolic root extract (200 and 300 mg / kg b.w.) was compared to standard thiazide drug treated group, showing no significant difference (p<0.05) and thus it proves that the ethanolic root extract of S.spontaneum exhibits potent antiurolithiatic activity.


Keyword:     Saccharum spontaneumLysosomal EnzymesThiazideGlycolic acid


Citation:

M. Sathya and R. Kokilavani. Effect of Saccharum spontaneum Linn. on Lysosomal enzymes of Uro-lithiatic rats. J App Pharm Sci. 2012; 2(9): 122-126.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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