Review Article | Volume : 2 Issue : 4, April 2012

Erythrocytes as Carrier for Drugs, Enzymes and Peptides

Srinu Ravilla Babu Rao Chandu Sreekanth Nama Nagaveni .B   

Open Access    DOI: 10.7324/JAPS.2012.2503

Abstract

Erythrocytes are potential biocompatible carriers for different drugs, peptide molecules and different enzymes. Now a day the method that is used for encapsulation of pharmaceuticals into the erythrocytes mainly based on the hypo-osmotic dialysis. Encapsulation of these drugs or enzymes or peptides into erythrocytes significantly changes the pharmacokinetic properties of drugs in both animals and humans, enhancing liver and spleen uptake and targeting the reticuloendothelial system. By the encapsulation of these into erythrocytes can be applied as targeted drug delivery systems. Erythrocytes are successful as carrier systems for different drugs, enzymes and peptide molecules. The result after using drug encapsulated in erythrocytes is more compared to the free form of the drug.


Keyword:     Drug loading methods carrier erythrocytes Applications Drugs Enzymes Peptides.


Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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