An overview on clinical studies of Morus species with bioactivities of compounds providing supporting evidence

Eric Wei Chiang Chan   

Open Access   

Published:  May 07, 2024

DOI: 10.7324/JAPS.2024.184245

Morus of the family Moraceae is a small plant genus having 19 species worldwide. Among the Morus species, M. alba (MA), M. indica, M. nigra, and M. rubra are economically important. Of these species, the medicinal values of the whole plant, leaf, fruit, twig, and root of MA are the most well-known. Most noteworthy are the anti-diabetic properties of MA. In this review, 23 clinical studies on anti-diabetic properties (5 in Japan) and 9 clinical studies on other pharmacological properties (4 in Thailand) of Morus species are described. The latter includes hypolipidemic, cognitive enhancement, coronary heart disease attenuation, anti-obesity, and climacteric improvement. Further studies on the molecular mechanisms of mulberry compounds, and their safety, distribution, absorption, metabolism, and excretion are needed.

Keyword:     Morus alba M. indica M. nigra mulberry anti-diabetic 1-deoxynojirimycin


Chan EWC. An overview on clinical studies of Morus species with bioactivities of compounds providing supporting evidence. J Appl Pharm Sci. 2024. Online First.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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