Immuno-stimulant effects of the dietary Spirulina (Spirulina Platensis) were studied in tilapia, Oreochromis niloticus. For this purpose, fish were fed with Spirulina and the parameters of non-specific defense mechanisms, including serum bacterial activity, phagocytosis and lysozyme activity were performed 1. 2. 3 and 4 weeks after Spirulina administration. The efficacy also determined by bacterial challenge and monitoring specific antibody levels (Microagglutination). The results indicated that Spirulina enhanced responses of bactericidal, phagocytic activity and lysozyme activity. Determined by micro-agglutination, antiserum of experimental fish displayed high antibody titers. The fish fed with Spirulina and vaccinated fish conferred protection against Aeromonas hydrophila challenge 80% and 70% relative percentage survival (RPS) respectively. These findings suggest that dietary Spirulina has immunostimulatory effects on the immune system of tilapia (O. niloticus).
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In vitro antiviral and antimicrobial activities of Spirulina platensis extract
Molecular studies of bioactive peptides of Nile tilapia (Oreochromis niloticus) skin protein hydrolysate DLBS3D33 as MMP-2 inhibitorSherlyn P. Wijaya, Puji Rahayu, Maggy T. Suhartono, Raymond Tjandrawinata