Research Article | Volume : 2 Issue : 2, February 2012

Immunostimulant effects of dietary Spirulina platensis on tilapia Oreochromis niloticus

Haney M. Ragap Rheyad H. Khalil Hawazin H. Mutawie   

Open Access   


Immuno-stimulant effects of the dietary Spirulina (Spirulina Platensis) were studied in tilapia, Oreochromis niloticus. For this purpose, fish were fed with Spirulina and the parameters of non-specific defense mechanisms, including serum bacterial activity, phagocytosis and lysozyme activity were performed 1. 2. 3 and 4 weeks after Spirulina administration. The efficacy also determined by bacterial challenge and monitoring specific antibody levels (Microagglutination). The results indicated that Spirulina enhanced responses of bactericidal, phagocytic activity and lysozyme activity. Determined by micro-agglutination, antiserum of experimental fish displayed high antibody titers. The fish fed with Spirulina and vaccinated fish conferred protection against Aeromonas hydrophila challenge 80% and 70% relative percentage survival (RPS) respectively. These findings suggest that dietary Spirulina has immunostimulatory effects on the immune system of tilapia (O. niloticus).

Keyword:     Spirulina platensis Oreochromis niloticus immune assay Phagocytic assay.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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