Review Article | Volume : 2 Issue : 1, January 2012

Novel Vesicular System: An Overview

Seema M. Jadhav Pournima Morey Mrs. Manisha Karpe Vilasrao Kadam   

Open Access   


Novel drug delivery attempts to either sustain drug action at a predetermined rate, or by maintaining a relatively constant, effective drug level in the body with concomitant minimization of undesirable side effects. The vesicular systems are highly ordered assemblies of one or several concentric lipid bilayer formed, when certain amphiphillic building blocks are confronted with water. The vesicular system such as liposomes, niosomes, sphingosomes, ethosomes, transferosomes and pharmacosomes are used to improve the therapeutic index of both existing and new drug molecules by encapsulating an active medicament inside vesicular structure in one such system. It prolongs the existence of the drug in systemic circulation and finally reduces the toxicity. Such different systems are widely used in gene delivery, tumor targeting, oral formulations, in stability and permeability problems of drugs. Now a days vesicle as a carrier system have become the vehicle of choice in drug delivery and lipid vesicles were found to be of value in immunology, membrane biology and diagnostic technique and most recently in genetic engineering.

Keyword:     Vesicular system controlled drug delivery stability applications.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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