Research Article | Volume: 8, Issue: 11, November, 2018

Analysis of acetaminophen, mefenamic acid, sibutramine hydrochloride, and sildenafil citrate

Eva Susanty Simaremare,  Rizka Agustine Susilowati,  Yeyen Dwi Astuti,  Rusadi Hermawan,  Elsye Gunawan,  Rani Dewi Pratiwi,  Rusnaeni   
Eva Susanty Simaremare, Rizka Agustine Susilowati, Yeyen Dwi Astuti, Rusadi Hermawan, Elsye Gunawan, Rani Dewi Pratiwi, Rusnaeni

Department of Pharmacy, Universitas Cenderawasih, Jayapura 99358, Indonesia.

Open Access   

Published:  Nov 30, 2018

DOI: 10.7324/JAPS.2018.81107
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Abstract

Jamu, Indonesia herbal medicine, has long been used for helping to heal many diseases. But nowadays, many of jamu were adulterated with chemical drugs that are harmful to consumers. Adulterations were analyzed in several places except in Papua Jayapura. We conducted an analysis of jamu which containing acetaminophen (ACE), mefenamic acid (MEFA), sibutramine hydrochloride (SH), and sildenafil citrate (SILC). Samples were taken by representing herbal that predicted containing chemicals. Thin-layer chromatography and UV-Vis spectrophotometry methods were used for quantitative analysis while the determination of concentration was used by titration and UV-Vis spectrophotometry methods. In this study, we reported that there was one sample in herbal medicines containing ACE, three samples containing MEFA, two samples of slimming herbal contained SH, and three samples of aphrodisiac herbal contained SILCs.


Keyword:     Acetaminophen mefenamic acid sibutramine hydrochloric sildenafil citrate Indonesia herbal medicines Jamu.

Citation:

Simaremare ES, Susilowati RA, Astuti YD, Hermawan R1, Gunawan E, Pratiwi RD, Rusnaeni. Analysis of acetaminophen, mefenamic acid, sibutramine hydrochloride, and sildenafil citrate. J Appl Pharm Sci, 2018; 8(11): 048–056.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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