Plants have provided a source of inspiration for novel drugs compounds, as plant derived medicines have made large contributions to human health and well-being. In present study, the methanolic, ethanolic, chloroformic and petroleum ether extracts of Sapium sebiferum leaves were investigated for their antifungal activity against Aspergillus niger and Aflatoxigenic Aspergillus flavus. Results obtained showed that all the extracts reduced colony growth by 1-32%. It was found that among all the leaf extracts, methanolic and ethanolic extracts have maximum percentage growth inhibition (26%) against Aspergillus flavus, while methanolic extracts showed maximum percentage growth inhibition (32%) against Aspergillus niger.
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