Review Article | Volume: 8, Issue: 3, March, 2018

Caesalpinia crista: A coastal woody climber with promising therapeutic values

Eric Wei Chiang Chan Joseph Tangah Shigeyuki Baba Hung Tuck Chan Mami Kainuma Tomomi Inoue   

Open Access   

Published:  Mar 30, 2018

DOI: 10.7324/JAPS.2018.8319

Caesalpinia crista L. is a scrambling coastal woody climber of the family Caesalpiniaceae. Leaves of C. crista are bipinnate with the rachis armed with spines beneath. Flowers are yellow and fragrant, bearing 5 petals. Pods are flat and have a beaked tip. Diterpenoids of the cassane and norcassane types are the major compounds isolated from C. crista. Seeds of C. crista yielded cassane diterpenoids such as caesalpinins and caesalmins, and norcassane diterpenoids such as norcaesalpinins. From the stems, roots and seeds, cassane diterpenoids (e.g. taepeenins A–L), and norcassane diterpenoids (e.g. nortaepeenins A & B) have been isolated. Flavonoids such as derivatives of flavones and flavanones have been isolated from aerial parts and flowers. Phenolic acids such as caffeic acid, chlorogenic acid, p-coumaric acid, ferulic acid and gallic acid have been identified from leaves. Pharmacological properties of C. crista include antioxidant, antibacterial, antiviral, anti-malarial, anti-tumour, anticancer, anti-diabetic, anti-inflammatory, analgesic, hepatoprotective, cardioprotective, anti-amyloidogenic, nootropic, wound healing, anthelmintic, insecticidal, antipyretic and antiulcer activities. In conclusion, properties of C. crista exhibit potential benefits to be used for pharmacological purposes.

Keyword:     Caesalpinia cristaPhytochemistryPharmacologyDiterpenoids.


Chan EWC, Tangah J, Baba S, Chan HT, Kainuma M, Inoue T. Caesalpinia crista: A coastal woody climber with promising therapeutic values. J App Pharm Sci, 2018; 8(03): 133-140.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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