Research Article | Volume: 7, Issue: 12, December, 2017

Socioeconomic position as a risk factor for BPA exposure in a sample of Egyptian children

Azza A. Gabr,  Nermine N. Mahfouz,  Mones M. Abu Shady,  Mai M. Youssef,  Ebtissam M. Salah El-Din,  Alyaa H Kamhawy,  Jihan Hussein,  Tarek S. Ibrahim,  M. A. Abbas   
Azza A. Gabr1, Nermine N. Mahfouz1, Mones M. Abu Shady1, Mai M. Youssef1, Ebtissam M. Salah El-Din1, Alyaa H Kamhawy1, Jihan Hussein2, Tarek S. Ibrahim1, M. A. Abbas1

1Child Health Department, Medical Division, National Research Centre (NRC), (33rd El Bohouth st, former El Tahrir st, Dokki, Cairo, Egypt.

2Medical Biochemistry Department, Medical Division, National Research Centre (NRC), (33rd El Bohouth st, former El Tahrir st, Dokki, Cairo, Egypt.

Open Access   

Published:  Dec 30, 2017

DOI: 10.7324/JAPS.2017.71211
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Abstract

Background: Bisphenol A is an endocrine-disrupting chemical that interferes with hormone action and contributes to disease and disability. Objective: To estimate the concentrations of urinary Bisphenol A in a sample of Egyptian children from different socioeconomic levels. Methods: A cross-sectional study included 167 children aged 2-18 years of both sexes. Socio-demographic data were evaluated and estimation of urinary Bisphenol A using high performance liquid chromatography was done. Urinary Bisphenol A, was categorized into quartiles (<1.3, 1.3–<2.6, 2.6–4.9, >4.9) ng/mL and was associated and analyzed with the social class. Results: The total urinary Bisphenol A ranged from 0.1 to 18.9 ng/ml with a mean 1.29 (+2.09), median 0.67 and geometric mean 0.68. According to parental occupation and education children were divided into 3 social classes: low (21.5%), middle (41.1%), and high (37.3 %). Children of high class have Bisphenol A levels significantly higher than middle and low classes, p=0.01. Conclusion: Urinary Bisphenol A concentrations exhibited low values in more than three fourths of the studied group indicating low exposure. The highest levels were detected in children from high socioeconomic standard. Excessive use of plastic bottles, microwave plastic wares and consumption of canned food may be the sources of exposure.


Keyword:     Bisphenol A children socioeconomic level exposure sources.

Citation:

Gabr AA, Mahfouz NN, Shady MMA, Youssef MM, El-Din EMS, Kamhawy AH, Hussein J, Ibrahim TS, Abbas MA. Socioeconomic position as a risk factor for BPA exposure in a sample of Egyptian children. J App Pharm Sci, 2017; 7 (12): 084- 089.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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