Short Communication | Volume: 7, Issue: 11, November, 2017

In vitro anti-Candida effect of (S)-(-)-citronellal

Heloísa Mara Batista Fernandes de Oliveira Abrahão Alves de Oliveira Filho José Pinto de Siqueira Júnior Edeltrudes Oliveira Lima   

Open Access   

Published:  Nov 30, 2017

DOI: 10.7324/JAPS.2017.71127
Abstract

The terpenoids forms a group of natural compounds with the great potential to develop the products for disease control. In this study, the monoterpene (S)-(-)-citronellal was evaluated for its antifungal effects. The five Candida albicans strains and five Candida tropicalis strains were used in the study. All the microorganism strains were obtained from the Laboratory of Mycology. The Microdilution method was used for antifungal assay of the monoterpene and the Nistatin (100 UI/mL) was used as standard drug. The results showed that the monoterpene presented MIC50 and MFC50 the values of 256 µg/mL, and 512 µg/mL, respectively for both species of fungi. The obtained results showed activity fungicide against both fungal strains.


Keyword:     Monoterpene Antifungal Candida tropicalis Candida albicans.


Citation:

deOliveira HMBF, Filho AAO, Lima EO, Júnior JPS. In vitro antiCandida effect of (S)-(-)-citronellal. J App Pharm Sci, 2017; 7 (11): 177-179.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text

Reference

Article Metrics
312 Views 23 Downloads 335 Total

Year

Month

Related Search

By author names