Research Article | Volume: 7, Issue: 8, August, 2017

Protective Effects of Chives Leaves (Allium Schoenoprasum, L.) Infusion Against Ethylene Glycol and Ammonium Chloride Induced Nephrolithiasis in rats

Ginda Haro Siti Morin Sinaga I. Iksen N. Nerdy Suthinee Theerachetmongkol   

Open Access   

Published:  Aug 30, 2017

DOI: 10.7324/JAPS.2017.70830
Abstract

The present day medical management of calculi is either costly or not without side effects. Hence, the search of anti-calculi drugs from natural sources has been assumed greater importance. Chives (Allium schoenoprasum L.) is a long-lived plant which is very easy to grow. It contained a variety of phytochemical compounds and various minerals. This aim of this research was to evaluate exposed of anti-calculi activity of fresh and dried chives leaves infuse on male albino Wistar rats using 0.75 % ethylene glycol and 2 % ammonium chloride induction method. Animals in treatment group are given 10 % of fresh and dried chives leaves infuse. Anticalculi activity in the chives leaves infuse examined by observing the kidney weight ratio, calcium level in kidney, urinary calcium level, urinary oxalate level, and creatinine serum level. From the data obtained, there were significant differences in treated group from negative control group. The biggest effect of dissolving the calcium oxalate crystal in kidney was the dried chives leaves infuse. Based on the above results, it could be concluded that chives leaves could be an alternative to calculi disease treatment.


Keyword:     Anticalculi Chives Infuse Ethylene Glycol Calcium Oxalate Atomic Absorption Spectrophotometry.


Citation:

Haro G, Sinaga SM, Iksen I, Nerdy N, Theerachetmongkol S. Protective Effects of Chives Leaves (Allium Schoenoprasum, L.) Infusion Against Ethylene Glycol and Ammonium Chloride Induced Nephrolithiasis in rats. J App Pharm Sci, 2017; 7 (08): 222-225.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text

Reference

Article Metrics
372 Views 38 Downloads 410 Total

Year

Month

Related Search

By author names