Research Article | Volume: 7, Issue: 5, May, 2017

Chemical Constituents of Hoya cagayanensis C. M. Burton

Consolacion Y. Ragasa ,  Melissa S. Borlagdan ,  Fernando B. Aurigue,  Robert Brkljača,  Sylvia Urban   
Consolacion Y. Ragasa1 & 2, Melissa S. Borlagdan1 & 3, Fernando B. Aurigue4, Robert Brkljača5, Sylvia Urban5

1Chemistry Department, De La Salle University, 2401 Taft Avenue, Manila 1004, Philippines.

2Chemistry Department, De La Salle University Science & Technology Complex Leandro V. Locsin Campus, Biñan City, Laguna 4024, Philippines.

3Food and Nutrition Research Institute- Department of Science and Technology, Bicutan, Taguig, Metro Manila, Philippines.

4Agriculture Research Section, Atomic Research Division, Philippine Nuclear Research Institute-Department of Science and Technology, Commonwealth Avenue, Diliman, Quezon City 1101, Philippines.

5School of Science (Discipline of Applied Chemistry and Environmental Science), RMIT University (City Campus), Melbourne 3001, Victoria, Australia.

Open Access   

Published:  May 30, 2017

DOI: 10.7324/JAPS.2017.70511
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Abstract

Chemical investigation of the dichloromethane extracts of Hoya cagayanensis led to the isolation of dihydrocanaric acid (1), lupeol (2), lupenone (3) and saturated hydrocarbons from the stems; and 2-hydroxyethyl benzoate (4) and a mixture of β-sitosterol (5a) and stigmasterol (5b) from the leaves. The structures of 1 and 4 were elucidated by extensive 1D and 2D NMR spectroscopy. The structures of 2, 3, 5a and 5b were identified by comparison of their NMR data with literature data.


Keyword:     Apocynaceae dihydrocanaric acid Hoya cagayanensis C. M. Burton 2-hydroxyethyl benzoate lupenone lupeol saturated hydrocarbons β-sitosterol stigmasterol.

Citation:

Ragasa C, Borlagdan M, Aurigue F, Brkljaca R, Urban S. Chemical Constituents of Hoya cagayanensis C. M. Burton. J App Pharm Sci, 2017; 7 (05): 061-065.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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