Mini Review | Volume: 7, Issue: 1, January, 2017

Potential drug interactions with cholinesterase inhibitors in Alzheimer patients: A guideline for Neurologists

Maryam Mehrpouya,  Sara Ataei,  Amir Nili-Ahmadabadi   
Maryam Mehrpouya1, Sara Ataei1, Amir Nili-Ahmadabadi2

1Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.

2Department of Pharmacology and Toxicology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran

Open Access   

Published:  Jan 31, 2017

DOI: 10.7324/JAPS.2017.70134
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Abstract

Cholinesterase inhibitors are used for the symptomatic treatment of patients with Alzheimer’s disease (AD). This population often has numerous comorbidities and is treated with multiple medications, which leads to polypharmacy. Possible pharmacokinetic and pharmacodynamic drug interactions may occur with this type of concomitant treatment, such as interactions with antipsychotics, antidepressants, anticholinergics, and cardiovascular and urinary disorder medications. Drug interactions should always be considered to reduce the risk of side effects and other problems for patients and also to increase the effectiveness of therapeutic drugs for AD.


Keyword:     Cholinesterase inhibitorsdrug interactionAlzheimer’s diseasepolypharmacy.

Citation:

Sara Ataei, Maryam Mehrpouya, Amir Nili-Ahmadabadi., Potential drug interactions with cholinesterase inhibitors in Alzheimer patients: A guideline for Neurologists. J App Pharm Sci, 2017; 7 (01): 223-226.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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