Research Article | Volume: 7, Issue: 5, May, 2017

Biological Activities of Plants used in Egyptian Ethnopharmacology

Khaled Rashed Maria Carmo Barreto   

Open Access   

Published:  May 30, 2017

DOI: 10.7324/JAPS.2017.70508
Abstract

In the present study, six plants traditionally used in Egypt for medical purposes were chosen: Diospyros lotus (Ebenaceae), Bauhinia alba (Fabaceae), Toona ciliata (Meliaceae), Alhagi maurorum (Fabaceae), Terminalia muelleri (Combretaceae) and Pistacia chinensis (Anacardiaceae). Methanol extracts of aerial parts from these plants were tested for biological activities that might corroborate their therapeutic potential. The strongest antioxidant activities, higher than or comparable to the standard compounds used, were presented by Terminalia muelleri and Pistacia chinensis (EC50 of 4.0 and 4.7 µg/mL for DPPH and 7.0 and 49.3 µg /mL for the FeCl3 reduction assay, respectively). These results strongly correlated with the polyphenol content of the extracts. Terminalia muelleri actively inhibited acetylcholinesterase (IC50=222.9 µg/mL), while the other extracts were not active in the range of concentrations tested. Alhagi maurorum presented cytotoxicity against all the cell lines tested, particularly against HeLa tumor cell line (EC50 = 16.8 µg /mL), with a SI (Selectivity Index) of 3 when compared with the control non tumor cell line.


Keyword:     Acetylcholinesterase inhibitors antioxidants cytotoxic activity antitumor agents polyphenol content.


Citation:

Rashed K, Barreto MC. Biological Activities of Plants used in Egyptian Ethnopharmacology. J App Pharm Sci, 2017; 7 (05): 046- 050.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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