Research Article | Volume: 6, Issue: 11, November, 2016

Antifungal activity of the cyanobacterium Microcystis aeruginosa against mycotoxigenic fungi

Diaa A. Marrez Yousef Y. Sultan   

Open Access   

Published:  Nov 29, 2016

DOI: 10.7324/JAPS.2016.601130
Abstract

Cyanobacteria are rich sources of bioactive compounds. In the present study, the antifungal activity of different solvent extracts of Microcystis aeruginosa was evaluated. Among these extracts, diethyl ether extract showed the highest antifungal activity against all tested mycotoxigenic fungi and gave inhibition zone ranged from 10.3 to 21.6 mm. In this direction, the fraction (F4) was the best fraction in antifungal activity against all tested fungi. Sub-fraction F4-10 was chosen as the highest sub-fraction had bioactivity. Using TLC bioautography, GC-MS and NMR; two antifungal compounds were isolated, purified and identified as Butylated Hydroxytoluene (BHT) and Hexadecanoic acid, methyl ester.


Keyword:     Microcystis aeruginosa Antifungal activity mycotoxigenic fungi TLC bioautography.


Citation:

Marrez DA, Sultan YY. Antifungal activity of the cyanobacterium Microcystis aeruginosa against mycotoxigenic fungi. J App Pharm Sci, 2016; 6 (11): 191-198.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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