Research Article | Volume: 6, Issue: 10, October, 2016
Research Article | Volume: 6, Issue: 10, October, 2016
Cu(II) and Ni(II) complexes of 2-butyl-4-chloro-5-formylimidazole thiosemicarbazone (L) are synthesized and characterized by using spectroscopic techniques like elemental analysis, FT-IR, mass spectrometry, electronic and EPR spectra. The complexes are found to have characteristic electronic spectra and the geometry of the complexes are identified as octahedron. Both the complexes are found to exhibit similar anti-microbial activity against the gram –ve and gram +ve bacteria. Anti-cancer activity against the cancer cell lines (MDA-MB 231 cell lines) among the compounds studied for % of viability, the inhibition concentration 50 values were shown by Cu(II)-L complex at 80 mg/ml and by Ni(II)-L complex at 100 mg/ml.
Reddy AS, Krishna LS, Rashmi HK, Devi PUM, Sarala Y., Reddy AV. Synthesis, spectroscopic characterization and biological applications of Cu(II) and Ni(II) complexes with 2-butyl-4-chloro5-formylimidazole thiosemicarbazone. J App Pharm Sci, 2016; 6 (10): 107-112.
Year
Month
Synthesis, spectroscopic characterization and antimicrobial activity studies of 2-Butyl-4-chloro-5-formylimidazole thiosemicarbazone and its manganese (II) complex
Phytochemical screening and Antimicrobial activity of the leaves of Memecylon umbellatum burm. F.
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