Research Article | Volume: 6, Issue: 8, August, 2016

Chemical composition and antibacterial activity of Piper lenticellosum C.D.C essential oil collected in Ecuador

María Eugenia Rondón,  Judith Velasco,  Xavier Cornejo,  Janeth Fernández,  Vladimir Morocho   
María Eugenia Rondón1, Judith Velasco2, Xavier Cornejo3, Janeth Fernández2, Vladimir Morocho3

1Facultad de Ciencias Naturales, Universidad de Guayaquil, Guayaquil, Ecuador. Facultad de Farmacia y Bioanálisis. Universidad de Los Andes, Mérida, Venezuela.

2Facultad de Farmacia y Bioanálisis. Universidad de Los Andes, Mérida, Venezuela.

3Herbario GUAY, Universidad de Guayaquil, Facultad de Ciencias Naturales, Guayaquil, Ecuador.

4Departamento de Química. Universidad Técnica Particular de Loja, Ecuador.

Open Access   

Published:  Aug 30, 2016

DOI: 10.7324/JAPS.2016.60824
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Abstract

The essential oil of the leaves and spikes of Piper lenticellosum C. DC. (Piperaceae) was isolated by hydrodistillation and analyzed by GC/MS. A yield of 2.06 % was obtained. Twenty eight components were identified by comparison of their mass spectra with Wiley GC-MS library data and the retention indices (RI) calculated for every compound. The major constituents were piperitone (33.97 %), 1,8 cineole (11.92 %), limonene (11.07 %), safrole (8.18 %) and α-pinene (4.49 %). Antibacterial activity of the essential oil was evaluated against five important human pathogenic bacterial strains using the disk diffusion agar method. The results showed at moderate activity against Staphylococcus aureus ATCC (25923), Escherichia coli ATCC (25922) and Klebsiella pneumoniae ATCC (233357) with minimal inhibitory concentration (MIC) values of 100, 200 y 300 µL/mL, respectively. According to the literature consulted, this is the first report on chemical composition and antibacterial activity of the essential oil of Piper lenticelosum C. DC. from Ecuador.


Keyword:     Piper lenticellosum Piperaceae piperitone essential oil antibacterial activity.

Citation:

Rondón ME, Velasco J, Cornejo X, Fernández J, Morocho W. Chemical composition and antibacterial activity of Piper lenticellosum C.D.C essential oil collected in Ecuador. J App Pharm Sci, 2016; 6 (08): 156-159.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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