Review Article | Volume: 6, Issue: 7, July, 2016

Pharmacological Effects of Atorvastatin in Platelet Function and Plaque Rupture

Pushpa Natarajan Suresh Kanna Sinu Sahl Pooja Sathish Vijaya Anand   

Open Access   

Published:  Jul 28, 2016

DOI: 10.7324/JAPS.2016.60728

Platelets are a prime reason for causing cardiovascular disease (CVD). After atherosclerotic plaque rupture, platelets can form pathogenic, formation of blood clot which leads to various cardiovascular events. The beneficial effect of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-Co-A) reductase inhibitors reduces CVDs clinically. The objective of this review is the pharmacological benefit of atorvastatin in CVD by platelets and plaque rupture due to high levels of cholesterol.

Keyword:     Atorvastatin Platelet aggregation Platelet function Cardiovascular disease.


Natarajan P, Kanna S, Sahl S, Sathish P, Anand V. Pharmacological Effects of Atorvastatin In Platelet Function and Plaque Rupture. J App Pharm Sci, 2016; 6 (07): 189-192.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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