Review Article | Volume: 6, Issue: 7, July, 2016

Pharmacological Effects of Atorvastatin in Platelet Function and Plaque Rupture

Pushpa Natarajan,  Suresh Kanna,  Sinu Sahl,  Pooja Sathish,  Vijaya Anand   
Pushpa Natarajan1, Suresh Kanna2, Sinu Sahl3, Pooja Sathish3, Vijaya Anand3

1Department of Microbiology, Cauvery College for Women, Tiruchirappalli, Tamil Nadu, India.

2Department of Chemistry, Bharathiyar College of Engineering and Technology, Karaikal, Puducherry, Tamil Nadu, India.

3Department of Human Genetics and Molecular Biology, Bharatiar University, Coimbatore, Tamil Nadu, India.

Open Access   

Published:  Jul 28, 2016

DOI: 10.7324/JAPS.2016.60728
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Abstract

Platelets are a prime reason for causing cardiovascular disease (CVD). After atherosclerotic plaque rupture, platelets can form pathogenic, formation of blood clot which leads to various cardiovascular events. The beneficial effect of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-Co-A) reductase inhibitors reduces CVDs clinically. The objective of this review is the pharmacological benefit of atorvastatin in CVD by platelets and plaque rupture due to high levels of cholesterol.


Keyword:     Atorvastatin Platelet aggregation Platelet function Cardiovascular disease.

Citation:

Natarajan P, Kanna S, Sahl S, Sathish P, Anand V. Pharmacological Effects of Atorvastatin In Platelet Function and Plaque Rupture. J App Pharm Sci, 2016; 6 (07): 189-192.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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