Short Communication | Volume: 6, Issue: 7, July, 2016

Potential radical-scavenging activity of Pouteria caimito leaves extracts

Cecilia Vilela França,  João Paulo Silvério Perfeito,  Inês Sabioni Resck,  Sueli Maria Gomes,  Christopher William Fagg,  Carlos Frederico Souza Castro,  Luiz Alberto Simeoni,  Dâmaris Silveira   
Cecilia Vilela França1, João Paulo Silvério Perfeito1, Inês Sabioni Resck2, Sueli Maria Gomes3, Christopher William Fagg3, Carlos Frederico Souza Castro4, Luiz Alberto Simeoni1, Dâmaris Silveira1

1Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Asa Norte, Brasília, DF, Brazil.

2Instituto de Química. Universidade de Brasilia, Campus Universitário Darcy Ribeiro, Asa Norte, Brasília, DF, Brazil.

3Departamento de Botânica, Instituto de Ciências Biológicas, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Asa Norte, Brasília, DF, Brazil.

4Departamento de Ensino de Graduação, Instituto Federal de Educação, Ciência e Tecnologia Goiano, Campus Rio Verde, Rod. Sul Goiana, Km 01, Setor Universitário Rio Verde, GO, Brazil.

Open Access   

Published:  Jul 28, 2016

DOI: 10.7324/JAPS.2016.60727
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Abstract

Pouteria caimito (Sapotaceae) is widely distributed throughout Latin America, including Brazil. The yellow fruits, known as abiu, caimito, or abiurana, are eaten in natura or used to prepare desserts. In addition to being a commercially available Brazilian fruit, P. caimito has also been used as a traditional medicine. Therefore, hexane, ethanol, and aqueous extracts from its leaves were evaluated for radical-scavenging activity. Free radical-scavenging activity was tested using the DPPH assay. Total phenolic and proanthocyanidin contents were also determined. The aqueous extract comprised the highest total phenol and proanthocyanidin contents (173.6 µg/mL) and showed the highest radical-scavenging activity (ED50= 36.1 µg/mL). Phytochemical analysis of the hexane extract allowed the isolation of spinasterol. We found a high correlation between total phenolic and proanthocyanidin contents and radical-scavenging activity. To our knowledge, this is the first time spinasterol has been isolated from P. caimito leaves.


Keyword:     Pouteria caimitoSapotaceaeCerradospinasterolanti-oxidante activity.

Citation:

França CV, Perfeito JPS, Resck IS, Gomes SM, Fagg CW, Castro CFS, Simeoni LA, Silveira D. Potential radical-scavenging activity of Pouteria caimito leaves extracts. J App Pharm Sci, 2016; 6 (07): 184-188.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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